Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   NR349_RS14780 Genome accession   NZ_CP102380
Coordinates   3040931..3041590 (+) Length   219 a.a.
NCBI ID   WP_262513199.1    Uniprot ID   -
Organism   Escherichia coli strain BM28     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3035931..3046590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NR349_RS14755 (NR349_14755) ygiS 3037214..3038821 (-) 1608 WP_001295629.1 ABC transporter substrate-binding protein -
  NR349_RS14760 (NR349_14760) mqsA 3038954..3039349 (-) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  NR349_RS14765 (NR349_14765) mqsR 3039351..3039647 (-) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  NR349_RS14770 (NR349_14770) ygiV 3039852..3040334 (-) 483 WP_000183505.1 GyrI-like domain-containing protein -
  NR349_RS14775 (NR349_14775) ygiW 3040387..3040779 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  NR349_RS14780 (NR349_14780) ciaR 3040931..3041590 (+) 660 WP_262513199.1 quorum sensing response regulator transcription factor QseB Regulator
  NR349_RS14785 (NR349_14785) qseC 3041587..3042936 (+) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  NR349_RS14790 (NR349_14790) ygiZ 3042982..3043314 (-) 333 WP_000917684.1 DUF2645 family protein -
  NR349_RS14795 (NR349_14795) mdaB 3043633..3044214 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  NR349_RS14800 (NR349_14800) ygiN 3044245..3044559 (+) 315 WP_000958598.1 putative quinol monooxygenase -
  NR349_RS14805 (NR349_14805) parE 3044607..3046499 (-) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24709.65 Da        Isoelectric Point: 6.9850

>NTDB_id=616390 NR349_RS14780 WP_262513199.1 3040931..3041590(+) (ciaR) [Escherichia coli strain BM28]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLSRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTMHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=616390 NR349_RS14780 WP_262513199.1 3040931..3041590(+) (ciaR) [Escherichia coli strain BM28]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGTCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCATGCATGGTATTGGTT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.885

100

0.393
  ciaR Streptococcus pneumoniae D39

37.885

100

0.393
  ciaR Streptococcus pneumoniae R6

37.885

100

0.393
  ciaR Streptococcus pneumoniae TIGR4

37.885

100

0.393
  ciaR Streptococcus mutans UA159

35.426

100

0.361