Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NQZ80_RS00185 Genome accession   NZ_CP102244
Coordinates   36892..37482 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli O7:H15 strain ST70     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 31892..42482
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ80_RS00170 (NQZ80_00170) ilvN 33143..33433 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  NQZ80_RS00175 (NQZ80_00175) - 34509..34991 (+) 483 WP_032159284.1 hypothetical protein -
  NQZ80_RS00180 (NQZ80_00180) - 35603..36730 (+) 1128 WP_033560712.1 hypothetical protein -
  NQZ80_RS00185 (NQZ80_00185) letA 36892..37482 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  NQZ80_RS00190 (NQZ80_00190) uhpB 37482..38984 (+) 1503 WP_024216304.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  NQZ80_RS00195 (NQZ80_00195) uhpC 38994..40313 (+) 1320 WP_001301991.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  NQZ80_RS00200 (NQZ80_00200) uhpT 40569..41960 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=615924 NQZ80_RS00185 WP_000633668.1 36892..37482(+) (letA) [Escherichia coli O7:H15 strain ST70]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=615924 NQZ80_RS00185 WP_000633668.1 36892..37482(+) (letA) [Escherichia coli O7:H15 strain ST70]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTAGAACCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAGCGTTGTAGCCCTGACGA
ACTGATTGCTGCGGTGCATACGGTTGCCACAGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTTGGCCTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGTATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378