Detailed information NTG0061583

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SCI_RS02345
• Genome accession: NC_022238
• Coordinates: 456370..457425 (+)
• Length: 351 a.a.
• NCBI ID: WP_020997642.1
• Uniprot ID: U2ZNX3
• Organism: Streptococcus constellatus subsp. pharyngis C1050
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 451370..462425

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCI_RS02315 (SCI_0461)	-	451890..452525 (-)	636	WP_003035211.1	YigZ family protein	-
SCI_RS02320 (SCI_0462)	comFA/cflA	452582..453883 (+)	1302	WP_020997640.1	DEAD/DEAH box helicase	Machinery gene
SCI_RS02325 (SCI_0463)	-	453880..454545 (+)	666	WP_006267632.1	ComF family protein	-
SCI_RS02330 (SCI_0464)	hpf	454624..455166 (+)	543	WP_006267638.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
SCI_RS02335 (SCI_0465)	rsmD	455363..455902 (+)	540	WP_020997641.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SCI_RS02340 (SCI_0466)	coaD	455892..456389 (+)	498	WP_006267255.1	pantetheine-phosphate adenylyltransferase	-
SCI_RS02345 (SCI_0467)	sepM	456370..457425 (+)	1056	WP_020997642.1	SepM family pheromone-processing serine protease	Regulator
SCI_RS02350 (SCI_0468)	-	457712..458269 (+)	558	WP_006267391.1	YutD family protein	-
SCI_RS02355 (SCI_0469)	rlmN	458303..459385 (+)	1083	WP_006269861.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SCI_RS02360 (SCI_0470)	-	459378..459896 (+)	519	WP_003070167.1	VanZ family protein	-
SCI_RS02365 (SCI_0471)	cclA/cilC	459891..460565 (-)	675	WP_020997643.1	A24 family peptidase	Machinery gene
SCI_RS02370 (SCI_0472)	-	460716..461243 (+)	528	WP_006267546.1	DNA starvation/stationary phase protection protein	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 38352.39 Da
• Isoelectric Point: 10.2387

>NTDB_id=61583 SCI_RS02345 WP_020997642.1 456370..457425(+) (sepM) [Streptococcus constellatus subsp. pharyngis C1050]
MEKSRTKFKKWPIVAVVGLLLLFMSFIVPLPYYIEVPGGAADVRQVLRVDNKVDKEKGSYNFVTVGIQHATFAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDISLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKDLIDYVGSQKIGSKVKVNYVEDGHKKSAIGKIIKLENGKNGIGISLIDRTEVTSNIPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTREVKKSNPKAKTNYETAL
AAAKKIKTKMKIVPVKTLQDAIDYLKSTKKS

Nucleotide

• Length: 1056 bp

>NTDB_id=61583 SCI_RS02345 WP_020997642.1 456370..457425(+) (sepM) [Streptococcus constellatus subsp. pharyngis C1050]
ATGGAAAAATCACGAACTAAATTTAAAAAATGGCCGATAGTGGCTGTAGTAGGGCTGCTTCTACTGTTCATGTCTTTTAT
AGTTCCTCTGCCTTATTACATTGAGGTGCCAGGTGGTGCAGCAGATGTTCGGCAAGTATTACGTGTAGATAATAAAGTGG
ATAAGGAAAAAGGTTCTTATAACTTTGTCACTGTTGGGATTCAGCATGCAACCTTTGCTCATTTGGTTTATGCTTGGTTG
ACTCCTTTTACAGATATTTATTCGGCGAAAGATCTGACTGGCGGAACTTCTGATAAAGAATATATGCGAATCAATCAATT
TTATATGGAAACATCACAAAACTTAGCCAAATATCAAGGGTTAAAAAAAGCAGGCAAGGATATTAGCTTGAAATATTTGG
GTGTTTATGTGTTGCAAGTTACCAAGAATTCAACCTTTAAAGGGATTCTAAATATTGCAGATACTGTGACAGGCGTGAAT
GATAAGACTTTCAACAGTTCAAAAGATTTGATTGATTATGTAGGCTCACAGAAAATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCATAAAAAATCTGCTATAGGTAAAATTATCAAACTTGAAAATGGGAAAAATGGAATTGGTATTAGCT
TAATTGACCGAACAGAAGTCACAAGTAATATACCAATTGAATTTTCAACAGCTGGGATTGGTGGACCAAGTGCGGGTTTG
ATGTTTAGCTTGGCGATTTATACACAGATTGCAGACCCGACATTGAGAGATGGCAGAAATATTGCTGGGACAGGATCGAT
TGACCGTGAAGGAAAAGTTGGTGATATTGGTGGGATTGATAAAAAAGTTGTTTCAGCAGCTAAAAATGGCGCAGAAATTT
TCTTTGCGCCAAATAATCCAGTTACCAGGGAAGTGAAAAAATCCAATCCTAAAGCGAAAACAAATTATGAGACAGCTTTG
GCAGCTGCTAAAAAAATTAAAACTAAAATGAAAATTGTACCTGTCAAGACCTTGCAAGACGCAATTGATTACCTCAAAAG
TACTAAAAAATCTTAA

Domains

Predicted by InterProScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (234-306)

• PDZ domain (PDZ_2) (133-195)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	63.372	98.006	0.621