Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   NQZ91_RS03730 Genome accession   NZ_CP102145
Coordinates   781864..783222 (-) Length   452 a.a.
NCBI ID   WP_257117887.1    Uniprot ID   -
Organism   Streptococcus suis strain DNS20     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 776864..788222
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ91_RS03700 (NQZ91_03700) - 777547..777936 (-) 390 WP_105122586.1 cytidine deaminase -
  NQZ91_RS03705 (NQZ91_03705) deoC 777923..778585 (-) 663 WP_105110904.1 deoxyribose-phosphate aldolase -
  NQZ91_RS03710 (NQZ91_03710) - 778602..779879 (-) 1278 WP_257117886.1 pyrimidine-nucleoside phosphorylase -
  NQZ91_RS03715 (NQZ91_03715) - 779876..780466 (-) 591 WP_105138219.1 class I SAM-dependent methyltransferase -
  NQZ91_RS03720 (NQZ91_03720) coaA 780575..781495 (+) 921 WP_170239177.1 type I pantothenate kinase -
  NQZ91_RS03725 (NQZ91_03725) rpsT 781554..781802 (+) 249 WP_170239180.1 30S ribosomal protein S20 -
  NQZ91_RS03730 (NQZ91_03730) ciaH 781864..783222 (-) 1359 WP_257117887.1 cell wall metabolism sensor histidine kinase WalK Regulator
  NQZ91_RS03735 (NQZ91_03735) ciaR 783212..783886 (-) 675 WP_105110909.1 response regulator transcription factor Regulator
  NQZ91_RS03740 (NQZ91_03740) rplT 784327..784686 (-) 360 WP_105110910.1 50S ribosomal protein L20 -
  NQZ91_RS03745 (NQZ91_03745) rpmI 784739..784939 (-) 201 WP_024375714.1 50S ribosomal protein L35 -
  NQZ91_RS03750 (NQZ91_03750) infC 784967..785473 (-) 507 WP_105161128.1 translation initiation factor IF-3 -
  NQZ91_RS03755 (NQZ91_03755) cmk 785669..786346 (-) 678 WP_105161127.1 (d)CMP kinase -
  NQZ91_RS03760 (NQZ91_03760) - 786355..786885 (-) 531 WP_105138224.1 SAG1386/EF1546 family surface-associated protein -
  NQZ91_RS03765 (NQZ91_03765) - 786934..787128 (+) 195 WP_105110914.1 ferredoxin -
  NQZ91_RS03770 (NQZ91_03770) - 787096..787605 (-) 510 WP_105138226.1 EbsA family protein -
  NQZ91_RS03775 (NQZ91_03775) - 787752..788006 (-) 255 WP_170239173.1 hypothetical protein -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 51361.74 Da        Isoelectric Point: 5.8101

>NTDB_id=615457 NQZ91_RS03730 WP_257117887.1 781864..783222(-) (ciaH) [Streptococcus suis strain DNS20]
MINKMRKLTKSDNFSYFIRYFAVFTLIFISMTAIIFQLMRSTMYRSTDIKFDKIKQHPDLVLNFAAARMLNPDSEIILQD
QSNQGNASANTLPDDTDGGPGEPIRLGTNFHVLLYNSAGELVNSDVFSGLSELAFDKESLKNVKEVSVEGPFGDDDFRYT
TLELPSEVMEKYSSLDLKYATICVNVSQIKMSIQTYERTVAIVMVSFWFISLFASLYLAQLSMRPILLSYQKQKDFVENA
SHELRTPLTVLQNRLEGLFRHPNATIIESSESIASSLAEVRNMRILTSNLLNLARRDDGFQIVMDDLDPQYLEEIFDNFN
IIAEESGKDLLVTNHIKQPIRTDKALLKQLLTIIFDNALKYTRDDGQISIQARVKDKFAYFTVADNGIGISQDDKTKVFD
RFYRVDKARTRQKGGFGLGLSLAKQISDSLKGEISIRDNQPTGTIFEIKIPR

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=615457 NQZ91_RS03730 WP_257117887.1 781864..783222(-) (ciaH) [Streptococcus suis strain DNS20]
ATGATCAATAAGATGAGAAAGCTCACCAAGTCGGACAATTTTTCCTACTTTATCCGCTATTTTGCCGTATTTACGCTGAT
TTTCATATCTATGACGGCCATTATTTTTCAACTGATGCGGTCTACCATGTATCGTAGTACAGATATCAAGTTTGACAAAA
TCAAGCAACATCCTGACTTGGTTTTGAATTTTGCGGCAGCTAGGATGCTGAATCCAGATTCGGAAATTATTCTTCAGGAC
CAGAGCAATCAAGGTAATGCAAGTGCGAATACTCTCCCAGATGATACTGATGGTGGTCCCGGTGAGCCCATTCGTTTGGG
AACCAATTTCCACGTACTCTTGTATAATTCTGCGGGTGAGCTAGTCAATTCTGATGTCTTCAGCGGTTTGTCTGAATTGG
CTTTTGATAAGGAAAGTTTGAAAAATGTAAAGGAAGTCAGCGTCGAAGGGCCATTTGGTGACGATGATTTCCGTTATACC
ACCCTGGAGTTGCCGAGTGAGGTAATGGAAAAATATTCGTCGCTAGACTTGAAATACGCGACTATCTGTGTCAATGTCAG
TCAGATTAAAATGTCTATTCAGACCTATGAGCGAACAGTGGCGATTGTCATGGTCTCCTTCTGGTTTATTTCGCTGTTTG
CCAGTCTTTATTTAGCTCAACTCAGTATGCGGCCAATTTTGCTGAGCTATCAAAAGCAGAAGGATTTTGTGGAGAATGCT
AGTCATGAGCTCAGGACACCACTGACTGTCCTACAGAATCGCCTAGAGGGGCTCTTCCGTCATCCCAATGCGACCATCAT
TGAATCCAGTGAAAGCATTGCCTCCAGTCTTGCTGAAGTGCGGAACATGCGGATTTTAACCAGTAATTTGCTGAATCTGG
CTCGGCGAGATGATGGTTTCCAGATTGTGATGGATGATTTGGATCCACAATATCTCGAGGAAATCTTTGACAATTTTAAC
ATTATCGCTGAAGAGAGTGGCAAGGATTTACTTGTTACGAATCATATTAAGCAGCCTATTCGGACAGATAAGGCCCTGCT
AAAACAACTCCTGACCATTATTTTTGATAATGCCTTGAAATATACAAGAGACGATGGACAAATTAGCATTCAGGCAAGAG
TAAAGGATAAATTTGCGTACTTTACAGTCGCGGACAATGGAATAGGAATTAGTCAGGATGATAAGACCAAGGTCTTCGAT
CGTTTTTATCGGGTAGATAAGGCTAGAACGCGACAAAAAGGTGGTTTTGGACTCGGCTTGTCCTTGGCTAAACAGATTAG
TGATTCCTTGAAGGGGGAAATTTCAATTCGTGATAACCAGCCAACAGGAACTATTTTTGAAATCAAGATACCGAGATAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(343-451)

His Kinase A (phospho-acceptor) domain (HisKA)

(233-299)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

47.228

99.779

0.471
  ciaH Streptococcus pneumoniae D39

47.228

99.779

0.471
  ciaH Streptococcus pneumoniae R6

47.228

99.779

0.471
  ciaH Streptococcus pneumoniae TIGR4

47.228

99.779

0.471
  ciaH Streptococcus mutans UA159

45.575

100

0.456