Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   LIO32_RS02105 Genome accession   NZ_CP085087
Coordinates   413151..414200 (+) Length   349 a.a.
NCBI ID   WP_012775295.1    Uniprot ID   A0A2K1T047
Organism   Streptococcus suis strain Ssuis_MA2     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 408151..419200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIO32_RS02070 - 408453..409547 (+) 1095 WP_171840758.1 sensor histidine kinase -
  LIO32_RS02075 - 409544..410146 (+) 603 WP_024405571.1 response regulator transcription factor -
  LIO32_RS02080 - 410454..410672 (+) 219 WP_024405570.1 YqgQ family protein -
  LIO32_RS02085 - 410672..411058 (+) 387 WP_004194735.1 rhodanese-like domain-containing protein -
  LIO32_RS02090 - 411115..411837 (+) 723 WP_024405569.1 hypothetical protein -
  LIO32_RS02095 rsmD 412147..412686 (+) 540 WP_014638485.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  LIO32_RS02100 coaD 412676..413164 (+) 489 WP_002939048.1 pantetheine-phosphate adenylyltransferase -
  LIO32_RS02105 sepM 413151..414200 (+) 1050 WP_012775295.1 SepM family pheromone-processing serine protease Regulator
  LIO32_RS02110 - 414388..415029 (+) 642 WP_024382386.1 YutD-like domain-containing protein -
  LIO32_RS02115 rlmN 415038..416150 (+) 1113 WP_012028433.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  LIO32_RS02120 - 416147..416674 (+) 528 WP_012027591.1 VanZ family protein -
  LIO32_RS02125 nadE 417915..418739 (-) 825 WP_004194617.1 ammonia-dependent NAD(+) synthetase -

Sequence

Protein


Download         Length: 349 a.a.        Molecular weight: 37761.83 Da        Isoelectric Point: 4.6112

>NTDB_id=615265 LIO32_RS02105 WP_012775295.1 413151..414200(+) (sepM) [Streptococcus suis strain Ssuis_MA2]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide


Download         Length: 1050 bp        

>NTDB_id=615265 LIO32_RS02105 WP_012775295.1 413151..414200(+) (sepM) [Streptococcus suis strain Ssuis_MA2]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(132-195)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(232-315)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2K1T047

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

60.807

99.427

0.605