Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   LIO31_RS05745 Genome accession   NZ_CP085086
Coordinates   1138326..1139705 (-) Length   459 a.a.
NCBI ID   WP_024383407.1    Uniprot ID   A0A0Z8JF15
Organism   Streptococcus suis strain Ssuis_MA6     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1133326..1144705
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIO31_RS05725 - 1134585..1135175 (-) 591 WP_074389908.1 class I SAM-dependent methyltransferase -
  LIO31_RS05730 coaA 1135284..1136204 (+) 921 WP_002935283.1 type I pantothenate kinase -
  LIO31_RS05735 rpsT 1136263..1136511 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  LIO31_RS05740 - 1136773..1138002 (-) 1230 WP_023369936.1 transglutaminase domain-containing protein -
  LIO31_RS05745 ciaH 1138326..1139705 (-) 1380 WP_024383407.1 cell wall metabolism sensor histidine kinase WalK Regulator
  LIO31_RS05750 ciaR 1139698..1140369 (-) 672 WP_024394126.1 response regulator transcription factor Regulator
  LIO31_RS05755 - 1140563..1140943 (-) 381 WP_023369940.1 hypothetical protein -
  LIO31_RS05760 - 1141328..1142530 (+) 1203 WP_319022933.1 IS110 family transposase -
  LIO31_RS05765 phoU 1142732..1143388 (-) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  LIO31_RS05770 pstB 1143417..1144175 (-) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51951.68 Da        Isoelectric Point: 6.8879

>NTDB_id=615221 LIO31_RS05745 WP_024383407.1 1138326..1139705(-) (ciaH) [Streptococcus suis strain Ssuis_MA6]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGTIQMAANIKDKLVCFTVIDNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=615221 LIO31_RS05745 WP_024383407.1 1138326..1139705(-) (ciaH) [Streptococcus suis strain Ssuis_MA6]
ATGCCTAAGCGATTTAAAAAATTAATGTACACAGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAACTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGGTTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAATCGACAGTTGCTATTGTTATGGTGTCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCAGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAAGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGATGATGGGA
CAATTCAAATGGCAGCTAATATCAAGGATAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATGCC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATCTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8JF15

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae D39

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae R6

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae TIGR4

49.127

99.782

0.49
  ciaH Streptococcus mutans UA159

49.231

99.129

0.488