Detailed information NTG0061519

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: SII_RS03920
• Genome accession: NC_022237
• Coordinates: 778718..779560 (+)
• Length: 280 a.a.
• NCBI ID: WP_020998618.1
• Uniprot ID: T1ZFA2
• Organism: Streptococcus intermedius C270
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 773718..784560

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SII_RS03895 (SII_0765)	-	775307..775645 (+)	339	WP_003072637.1	ATP cone domain-containing protein	-
SII_RS03900 (SII_0766)	rpsU	775794..775970 (+)	177	WP_000048054.1	30S ribosomal protein S21	-
SII_RS03905 (SII_0767)	ylqF	776375..777226 (+)	852	WP_020998615.1	ribosome biogenesis GTPase YlqF	-
SII_RS03910 (SII_0768)	-	777213..777989 (+)	777	WP_020998616.1	ribonuclease HII	-
SII_RS03915 (SII_0769)	-	778078..778635 (+)	558	WP_020998617.1	sugar O-acetyltransferase	-
SII_RS03920 (SII_0770)	dprA/cilB/dalA	778718..779560 (+)	843	WP_020998618.1	DNA-processing protein DprA	Machinery gene
SII_RS03925 (SII_0771)	topA	779646..781739 (+)	2094	WP_148290354.1	type I DNA topoisomerase	-
SII_RS03930 (SII_0772)	-	781796..782290 (+)	495	WP_020998620.1	hypothetical protein	-
SII_RS03935 (SII_0773)	trmFO	782384..783718 (+)	1335	WP_020998621.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31115.65 Da
• Isoelectric Point: 5.6463

>NTDB_id=61519 SII_RS03920 WP_020998618.1 778718..779560(+) (dprA/cilB/dalA) [Streptococcus intermedius C270]
MNNFDIYKLKEAGLTNQQVINVLEYAEIHEKDLSAKGMAVVSECRNPALFIEKYLQLDDDLLRQEFEKFPSFSILDDVYP
WDLSEIYNPPVLLFYKGNLDLLKLPKVAVVGSRNSSRVGSQSVQKIIKELNNELVIVSGLARGIDTSAHMAALQNGGRTI
AVIGTGLDVFYPRANKKLQSYLGEHHLVLSEYGPEAEPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGRSDGCHHLIQEGAKCITSGSDVLSEFQF

Nucleotide

• Length: 843 bp

>NTDB_id=61519 SII_RS03920 WP_020998618.1 778718..779560(+) (dprA/cilB/dalA) [Streptococcus intermedius C270]
ATGAATAATTTTGATATTTATAAATTAAAAGAAGCCGGCTTGACAAACCAACAAGTTATCAATGTATTAGAATATGCTGA
AATACATGAAAAAGATTTGTCTGCCAAAGGCATGGCAGTTGTTTCCGAATGCCGTAATCCTGCTCTTTTTATTGAAAAAT
ATTTGCAGTTAGATGATGATTTATTACGTCAAGAATTTGAGAAATTCCCATCCTTTTCTATCTTGGACGATGTATATCCT
TGGGATTTGAGTGAAATTTATAATCCACCCGTTCTTCTTTTTTATAAAGGTAATTTGGATTTGCTAAAATTACCTAAAGT
GGCTGTTGTAGGAAGTCGGAATAGTAGCCGAGTAGGCAGTCAATCTGTTCAAAAGATTATTAAAGAGCTAAACAATGAAT
TGGTTATTGTGAGTGGTTTAGCACGCGGAATTGATACCTCGGCTCACATGGCAGCGTTGCAAAATGGTGGTCGAACAATT
GCAGTTATCGGAACGGGCCTAGATGTGTTTTACCCAAGGGCGAATAAGAAACTCCAATCGTATTTGGGAGAACATCATCT
AGTGCTTAGTGAGTATGGTCCTGAAGCAGAGCCATTAAAATTTCATTTTCCAGAGCGTAATCGGATTATAGCAGGATTGT
GTAGAGGGGTTATTGTCGCTGAAGCTAAAATGCGCTCAGGCAGCCTTATTACTTGTGAGCGAGCAATGGAAGAAGGGCGA
GATGTATTTGCTATTCCAGGGTCAATTTTAGATGGAAGAAGTGATGGCTGTCATCATTTGATTCAGGAGGGAGCAAAATG
CATTACATCAGGGTCTGACGTACTTTCTGAATTCCAGTTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-60)

3D structure

• AlphaFold DB: T1ZFA2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	76.429	100	0.764
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	76.071	100	0.761
dprA/cilB/dalA	Streptococcus pneumoniae D39	76.071	100	0.761
dprA/cilB/dalA	Streptococcus pneumoniae R6	76.071	100	0.761
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	76.071	100	0.761
dprA/cilB/dalA	Streptococcus mitis SK321	75.714	100	0.757
dprA	Streptococcus mutans UA159	65	100	0.65
dprA	Lactococcus lactis subsp. cremoris KW2	57.143	100	0.571
dprA	Legionella pneumophila strain ERS1305867	43.154	86.071	0.371
dprA	Bacillus subtilis subsp. subtilis str. 168	48.095	75	0.361