Detailed information NTG0615163

Bioinformatically predicted

Overview

• Name: comFA/cflA
• Type: Machinery gene
• Locus tag: LIO34_RS03130
• Genome accession: NZ_CP085085
• Coordinates: 596948..598240 (+)
• Length: 430 a.a.
• NCBI ID: WP_172005895.1
• Uniprot ID: -
• Organism: Streptococcus suis strain Ssuis_MA8
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	594782..595984	596948..598240	flank	964

Gene organization within MGE regions

Location: 594782..598240

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LIO34_RS03120	-	594782..595984 (+)	1203	WP_009909264.1	IS110-like element ISSsu7 family transposase	-
LIO34_RS03125	-	596259..596891 (-)	633	WP_004194123.1	YigZ family protein	-
LIO34_RS03130	comFA/cflA	596948..598240 (+)	1293	WP_172005895.1	DEAD/DEAH box helicase	Machinery gene

Sequence

Protein

• Length: 430 a.a.
• Molecular weight: 48884.49 Da
• Isoelectric Point: 9.2762

>NTDB_id=615163 LIO34_RS03130 WP_172005895.1 596948..598240(+) (comFA/cflA) [Streptococcus suis strain Ssuis_MA8]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFKEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYQAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNLLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQIAGRVGRSIERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide

• Length: 1293 bp

>NTDB_id=615163 LIO34_RS03130 WP_172005895.1 596948..598240(+) (comFA/cflA) [Streptococcus suis strain Ssuis_MA8]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTAAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTACATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCAAGCAGCAGACAATGCGGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACAGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACAGGTAAATTAAGTCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCTACTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTCCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CTAATCATTACCTCTACACAGCGTCAAGTCTTGTTCAGATTGCAGGCCGGGTCGGAAGGAGTATAGAACGTCCGACTGGT
TTACTTCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

• Helicase conserved C-terminal domain (Helicase_C) (289-393)

• Type III restriction enzyme, res subunit (ResIII) (91-235)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA/cflA	Streptococcus mitis NCTC 12261	66.821	100	0.67
comFA/cflA	Streptococcus pneumoniae Rx1	66.125	100	0.663
comFA/cflA	Streptococcus pneumoniae D39	66.125	100	0.663
comFA/cflA	Streptococcus pneumoniae R6	66.125	100	0.663
comFA/cflA	Streptococcus pneumoniae TIGR4	66.125	100	0.663
comFA/cflA	Streptococcus mitis SK321	65.661	100	0.658
comFA	Lactococcus lactis subsp. cremoris KW2	53.904	92.326	0.498
comFA	Latilactobacillus sakei subsp. sakei 23K	38.283	100	0.384
comFA	Bacillus subtilis subsp. subtilis str. 168	37.349	96.512	0.36