Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LG319_RS04520 Genome accession   NZ_CP085027
Coordinates   907064..907693 (+) Length   209 a.a.
NCBI ID   WP_053025469.1    Uniprot ID   -
Organism   Staphylococcus haemolyticus strain SLM-175     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 902064..912693
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LG319_RS04490 (LG319_04465) - 902909..903058 (-) 150 WP_245151289.1 hypothetical protein -
  LG319_RS04495 (LG319_04470) - 903191..903628 (-) 438 Protein_882 SDR family NAD(P)-dependent oxidoreductase -
  LG319_RS04500 (LG319_04475) - 903700..904593 (-) 894 Protein_883 HoxN/HupN/NixA family nickel/cobalt transporter -
  LG319_RS04505 (LG319_04480) - 904919..905305 (+) 387 WP_053025474.1 hypothetical protein -
  LG319_RS04510 (LG319_04485) liaF 905330..906031 (+) 702 WP_053025472.1 cell wall-active antibiotics response protein LiaF -
  LG319_RS04515 (LG319_04490) vraS 906028..907074 (+) 1047 WP_053025471.1 sensor histidine kinase Regulator
  LG319_RS04520 (LG319_04495) vraR 907064..907693 (+) 630 WP_053025469.1 two-component system response regulator VraR Regulator
  LG319_RS04525 (LG319_04500) - 907756..908967 (-) 1212 WP_053025467.1 YihY/virulence factor BrkB family protein -
  LG319_RS04530 (LG319_04505) - 909166..909450 (-) 285 WP_053025464.1 YtxH domain-containing protein -
  LG319_RS04535 (LG319_04510) - 909456..909920 (-) 465 WP_053025462.1 low molecular weight protein-tyrosine-phosphatase -
  LG319_RS04540 (LG319_04515) - 910062..910271 (+) 210 WP_011275380.1 DUF1128 domain-containing protein -
  LG319_RS04545 (LG319_04520) - 910285..911532 (+) 1248 WP_053025460.1 aminopeptidase -
  LG319_RS04550 (LG319_04525) - 911565..912098 (+) 534 WP_011275382.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23533.20 Da        Isoelectric Point: 5.1569

>NTDB_id=614718 LG319_RS04520 WP_053025469.1 907064..907693(+) (vraR) [Staphylococcus haemolyticus strain SLM-175]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEIVGEGESGKDAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKGLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIADAVRKTYNGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=614718 LG319_RS04520 WP_053025469.1 907064..907693(+) (vraR) [Staphylococcus haemolyticus strain SLM-175]
ATGACGATTAAAGTTTTGTTCGTTGATGACCATGAAATGGTTAGAATTGGGATATCAAGTTATCTATCAACACAATCTGA
CATTGAGATAGTTGGAGAAGGGGAATCTGGTAAAGATGCCATTGCAAAAGCTCATGAATTAAAACCTGATTTAATTCTTA
TGGATTTATTAATGGATGACATGGATGGCGTTGAAGCAACTACTCAAATCAAAAAAGGTTTGCCACATATTAAAGTTGTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATAGAGCATTAGATGCTGGTGTAGATAGCTATATTTTAAAAACGAC
TAGTGCTAGTGATATAGCCGACGCAGTACGCAAAACTTATAATGGTGAATCTGTATTTGAACCTGAAGTTTTAGTTAAGA
TGCGTAACAGAATGAAGAAACGTGCAGAATTATATGAAATGCTGACTGAGCGTGAAATGGAAATTTTATTATTAATTGCA
AAAGGGTATTCAAATCAAGAAATAGCGAGTGCTTCTCATATTACAATTAAAACCGTTAAAACTCATGTAAGTAATATATT
GAGTAAATTAGAAGTACAAGATAGAACACAAGCCGTAATTTATGCATTCCAACATAATTTGATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364