Detailed information NTG0614717

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LG319_RS04515
• Genome accession: NZ_CP085027
• Coordinates: 906028..907074 (+)
• Length: 348 a.a.
• NCBI ID: WP_053025471.1
• Uniprot ID: -
• Organism: Staphylococcus haemolyticus strain SLM-175
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 901028..912074

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LG319_RS04485 (LG319_04460)	map	901905..902657 (+)	753	WP_053025476.1	type I methionyl aminopeptidase	-
LG319_RS04490 (LG319_04465)	-	902909..903058 (-)	150	WP_245151289.1	hypothetical protein	-
LG319_RS04495 (LG319_04470)	-	903191..903628 (-)	438	Protein_882	SDR family NAD(P)-dependent oxidoreductase	-
LG319_RS04500 (LG319_04475)	-	903700..904593 (-)	894	Protein_883	HoxN/HupN/NixA family nickel/cobalt transporter	-
LG319_RS04505 (LG319_04480)	-	904919..905305 (+)	387	WP_053025474.1	hypothetical protein	-
LG319_RS04510 (LG319_04485)	liaF	905330..906031 (+)	702	WP_053025472.1	cell wall-active antibiotics response protein LiaF	-
LG319_RS04515 (LG319_04490)	vraS	906028..907074 (+)	1047	WP_053025471.1	sensor histidine kinase	Regulator
LG319_RS04520 (LG319_04495)	vraR	907064..907693 (+)	630	WP_053025469.1	two-component system response regulator VraR	Regulator
LG319_RS04525 (LG319_04500)	-	907756..908967 (-)	1212	WP_053025467.1	YihY/virulence factor BrkB family protein	-
LG319_RS04530 (LG319_04505)	-	909166..909450 (-)	285	WP_053025464.1	YtxH domain-containing protein	-
LG319_RS04535 (LG319_04510)	-	909456..909920 (-)	465	WP_053025462.1	low molecular weight protein-tyrosine-phosphatase	-
LG319_RS04540 (LG319_04515)	-	910062..910271 (+)	210	WP_011275380.1	DUF1128 domain-containing protein	-
LG319_RS04545 (LG319_04520)	-	910285..911532 (+)	1248	WP_053025460.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40180.57 Da
• Isoelectric Point: 5.8508

>NTDB_id=614717 LG319_RS04515 WP_053025471.1 906028..907074(+) (vraS) [Staphylococcus haemolyticus strain SLM-175]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSILAYKINQQNQWIKS
QIEHAIEGETVGINDQNIELYNETIDLYQTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMVQESQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVIHDI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNREDDNNDD

Nucleotide

• Length: 1047 bp

>NTDB_id=614717 LG319_RS04515 WP_053025471.1 906028..907074(+) (vraS) [Staphylococcus haemolyticus strain SLM-175]
ATGAACCACTACTTAAGAGCTATCGGTTCAATGCTTATACTAGTTTATAGCATGTTAACCGCGTTCTTATTTATAGATAA
AGTATTTGTTAATATTATCTACTTCCAAGGTATGTTTTATACTCAAATTTTTGGGATACCTGTTTTTCTATTTTTAAATT
TAGTCATCATTTTACTTTGTATTATTGTAGGTTCAATTCTCGCATATAAAATTAATCAACAAAATCAGTGGATTAAGTCA
CAAATTGAACATGCCATTGAAGGAGAAACAGTAGGTATTAATGATCAAAATATTGAGCTTTATAACGAAACCATAGACCT
TTATCAAACATTAGTTCCGCTAAATCAAGAGTTGCACCGTTTACGAATGAAAACGCAAAACTTAACTAATGAAAATTACA
ATATGAATGATGTCAAAGTTAAGAAAATCATTGAGGATGAACGACAGAGATTAGCTCGCGAGTTACACGACTCTGTAAGT
CAACAACTTTTTGCAGCAAGTATGATGTTATCTGCAATAAAAGAAACAAAGTTAGAGGCACCGCTTGATCAACAAATACC
AGTTTTAGAGAAAATGGTTCAGGAGTCTCAACTTGAAATGCGCGCATTATTACTTCATTTAAGACCTTTAGGTCTAAAAG
ATAAATCACTAGGTGAAGGTATCAAAGATTTAGTTATTGATTTGCAAAAGAAAGTGCCTATGAAAGTCATACACGATATT
CAAGATTTCAAGGTGCCTAAAGGTATAGAAGATCATTTATTTAGAATTACACAAGAGGCTATATCAAATACGTTAAGACA
TTCAAATGGAACTAAAGTCACAGTGGAATTATTTAACCAACAAGATTATCTATTACTTCGAATTCAAGACAATGGTAAAG
GATTCAATGTTGACGAGAAATTAGAGCAAAGTTATGGATTAAAAAATATGAGAGAACGCGCATTAGAAATTGGTGCGACA
TTCCATATTGTATCGTTACCGGATTCTGGAACGAGAATAGAAGTTAAAGCACCGTTAAATAGGGAGGATGATAATAATGA
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	91.931	99.713	0.917