Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   NPS17_RS09735 Genome accession   NZ_CP101985
Coordinates   2042458..2044413 (-) Length   651 a.a.
NCBI ID   WP_258969006.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14R     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2037458..2049413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS17_RS09710 (NPS17_09710) spx 2037960..2038358 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  NPS17_RS09715 (NPS17_09715) recA 2038443..2039594 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  NPS17_RS09720 (NPS17_09720) cinA 2039634..2040890 (-) 1257 WP_002266115.1 competence/damage-inducible protein A Machinery gene
  NPS17_RS09725 (NPS17_09725) - 2041039..2041599 (-) 561 WP_258969005.1 DNA-3-methyladenine glycosylase I -
  NPS17_RS09730 (NPS17_09730) ruvA 2041681..2042274 (-) 594 WP_002266975.1 Holliday junction branch migration protein RuvA Machinery gene
  NPS17_RS09735 (NPS17_09735) hexB 2042458..2044413 (-) 1956 WP_258969006.1 DNA mismatch repair endonuclease MutL Machinery gene
  NPS17_RS09740 (NPS17_09740) - 2044638..2044916 (+) 279 Protein_1873 transposase -
  NPS17_RS09745 (NPS17_09745) hexA 2044911..2047460 (-) 2550 WP_002271567.1 DNA mismatch repair protein MutS Machinery gene
  NPS17_RS09750 (NPS17_09750) - 2047453..2047800 (-) 348 WP_002264540.1 YlbF family regulator -
  NPS17_RS09755 (NPS17_09755) argR 2047797..2048234 (-) 438 WP_002262400.1 arginine repressor -
  NPS17_RS09760 (NPS17_09760) - 2048658..2049086 (-) 429 WP_226718080.1 cyclic nucleotide-binding domain-containing protein -

Sequence

Protein


Download         Length: 651 a.a.        Molecular weight: 73786.51 Da        Isoelectric Point: 6.5175

>NTDB_id=613798 NPS17_RS09735 WP_258969006.1 2042458..2044413(-) (hexB) [Streptococcus mutans strain COCC33-14R]
MSKIVELPEVLANQIAAGEVIERPASVVKELVENAIDADSSQITIEIEESGLKKIQVIDNGQGIEQADVIMSLRRHATSK
IKKQSDLFRIRTLGFRGEALPSIASISRLTLKTATKGEIHGTLVIANGGKIEKEEAISTPIGTKVSVENLFFNTPARLKY
MKSLQAELAHIIDVINRLSLAHPEIAFTLINDGRELTKTSGKGDLRQALAGIYGVTTAKKMVEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMNLISS
AIADSLREQELIPDALENLAKTSTNKKQKFEQTQLPLKQSNLYYDKTQNDFFLKETTVSEASSEFTVVDKAVKITDNVSG
HSSVKYAQRQMRTCENKEHPSLTMTDKQQKRQLSRIVESLENEEKSTFPELEYFGQMHGTYLFAQGEGGLYIIDQHAAQE
RVKYEYYRDKIGEVDNSLQQLLVPYLFEFPANDFMTLQEKMSILNEVGVHLENYGENTFILREHPIWLQEKEIESAVYEM
CDMLLLTNEVSIKKYRAELAIMMSCKRSIKANHTLDDYSARNLLIQLSQCKNPYNCPHGRPVLVNFTKADMEKMFRRIQE
NHTSLRELGKY

Nucleotide


Download         Length: 1956 bp        

>NTDB_id=613798 NPS17_RS09735 WP_258969006.1 2042458..2044413(-) (hexB) [Streptococcus mutans strain COCC33-14R]
ATGTCAAAAATTGTTGAACTGCCAGAAGTTTTAGCCAATCAAATTGCTGCTGGAGAGGTTATTGAAAGACCAGCTAGTGT
CGTAAAAGAACTAGTTGAGAATGCTATTGACGCTGATAGCAGCCAAATTACAATAGAAATTGAAGAATCAGGACTGAAAA
AAATTCAAGTGATTGATAATGGTCAAGGAATAGAACAAGCGGATGTAATTATGAGCTTACGTCGCCATGCAACTAGTAAG
ATTAAAAAACAATCCGATCTTTTTAGAATTAGGACCTTAGGTTTTAGAGGTGAGGCCCTTCCATCAATTGCTTCTATTAG
CAGACTAACATTAAAAACAGCAACAAAAGGGGAAATACATGGCACTTTAGTAATCGCAAATGGAGGTAAAATTGAAAAAG
AAGAAGCCATTAGTACCCCTATTGGAACCAAAGTGAGTGTTGAAAATCTTTTCTTCAATACCCCTGCTCGCCTTAAATAT
ATGAAAAGTTTGCAGGCAGAGCTTGCTCATATTATTGATGTTATTAACCGTCTTAGCTTGGCGCATCCCGAAATTGCTTT
CACGCTTATTAATGATGGCCGTGAATTAACAAAGACGTCAGGTAAAGGCGATCTGCGTCAAGCTTTAGCAGGTATTTATG
GGGTAACCACTGCTAAAAAAATGGTCGAAATTTCAAATGCAGATCTTGATTTTGAGGTATCTGGTTATATTAGTTTGCCT
GAATTAACCCGAGCTAATCGCAATTATATTACCATTCTTATTAATGGGCGTTATATCAAAAATTTTTTGCTCAATCGTGC
TATTCTTGATGGTTATGGTTCAAAATTAATGGTGGGACGTTTTCCAATTGCTGTTATTGATATTCAGATTGACCCTTATT
TAGCAGATGTTAATGTTCATCCAACTAAGCAGGAAGTTCGCATTTCTAAAGAAAAAGAGTTAATGAATCTCATTAGTTCG
GCAATTGCAGATAGTTTAAGAGAACAAGAGTTAATTCCTGATGCTTTGGAAAATCTTGCTAAAACTAGCACAAACAAGAA
ACAAAAGTTTGAACAAACACAGCTTCCTCTTAAACAATCAAATCTTTACTATGATAAGACTCAAAATGACTTCTTTCTCA
AAGAAACGACAGTTTCAGAAGCATCAAGCGAGTTTACAGTAGTTGATAAAGCTGTAAAAATTACTGATAATGTATCAGGA
CATAGCAGTGTAAAATATGCTCAACGTCAAATGAGAACTTGTGAAAACAAAGAGCATCCAAGTCTTACTATGACAGATAA
GCAACAAAAGCGACAGCTTAGTAGAATTGTTGAAAGTCTAGAAAATGAAGAAAAGTCAACTTTTCCTGAGTTAGAATATT
TTGGTCAAATGCATGGAACTTACCTCTTTGCTCAAGGTGAAGGGGGGCTTTATATCATAGATCAACATGCTGCTCAAGAA
CGTGTTAAATATGAATATTATCGTGATAAAATTGGAGAAGTAGACAATAGTTTACAGCAGCTTTTAGTACCTTATCTTTT
TGAATTTCCTGCTAATGATTTTATGACCTTACAAGAAAAAATGAGCATTTTAAATGAGGTTGGAGTTCACTTAGAAAACT
ATGGAGAGAATACTTTCATTTTGAGAGAACATCCTATTTGGTTACAGGAAAAAGAAATTGAATCAGCCGTTTATGAGATG
TGTGACATGTTGCTGTTGACAAATGAAGTCTCCATTAAGAAATATCGAGCGGAATTAGCTATTATGATGTCTTGCAAGCG
TTCTATCAAGGCTAATCATACTTTGGATGATTATTCTGCCAGAAATCTCTTAATTCAATTATCACAGTGCAAAAATCCTT
ACAATTGTCCTCATGGACGTCCTGTGCTTGTGAATTTCACAAAAGCTGATATGGAAAAGATGTTTCGTCGCATTCAGGAA
AACCATACTAGTTTGAGAGAATTAGGGAAATACTGA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-135)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

MutL C terminal dimerisation domain (MutL_C)

(453-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.757

100

0.705