Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   EL263_RS07370 Genome accession   NZ_AP018938
Coordinates   1391407..1393365 (-) Length   652 a.a.
NCBI ID   WP_000748873.1    Uniprot ID   P0A4G0
Organism   Streptococcus pneumoniae strain ATCC 49619     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1386407..1398365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL263_RS07345 (SPAT_1399) - 1387135..1388301 (-) 1167 WP_000521384.1 MalY/PatB family protein -
  EL263_RS07350 (SPAT_1400) - 1388309..1389403 (-) 1095 WP_000031968.1 cystathionine gamma-synthase -
  EL263_RS07355 (SPAT_1401) - 1389561..1390148 (-) 588 WP_306765881.1 ATP-binding cassette domain-containing protein -
  EL263_RS11830 - 1390142..1391235 (-) 1094 Protein_1401 ABC transporter ATP-binding protein -
  EL263_RS07370 (SPAT_1404) amiA 1391407..1393365 (-) 1959 WP_000748873.1 peptide ABC transporter substrate-binding protein Regulator
  EL263_RS07375 (SPAT_1405) - 1393568..1395190 (-) 1623 WP_000017796.1 polysaccharide biosynthesis protein -
  EL263_RS07380 (SPAT_1406) - 1395296..1396741 (+) 1446 WP_044811689.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  EL263_RS07385 (SPAT_1407) - 1396787..1396981 (-) 195 WP_000051195.1 CsbD family protein -
  EL263_RS07390 (SPAT_1408) - 1397082..1397731 (-) 650 Protein_1406 DUF1803 domain-containing protein -
  EL263_RS07395 (SPAT_1409) - 1397715..1398227 (-) 513 WP_000892252.1 YiiX/YebB-like N1pC/P60 family cysteine hydrolase -

Sequence

Protein


Download         Length: 652 a.a.        Molecular weight: 72561.97 Da        Isoelectric Point: 4.9968

>NTDB_id=61234 EL263_RS07370 WP_000748873.1 1391407..1393365(-) (amiA) [Streptococcus pneumoniae strain ATCC 49619]
MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPSSLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSL
AEDWTVSQDGLTYTYKLRKDAKWFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFLMKALVSKSAIEYKKNPNYWDAK
NVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFPNSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTS
DIEKKSTQEAVLNKNFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYGKEWQGINF
ADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGVSSIKQSIESVLGSDNVVIDIQQLTSDEFDS
SGYFAQTAAQKDYDLYHGGWGPDYQDPSTYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKR
YEKYADIQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDEYAKAREKWLKEKEESN
KKAQEELAKHVK

Nucleotide


Download         Length: 1959 bp        

>NTDB_id=61234 EL263_RS07370 WP_000748873.1 1391407..1393365(-) (amiA) [Streptococcus pneumoniae strain ATCC 49619]
ATGAAAAAGTCTAAGAGCAAATATCTAACCTTGGCAGGTCTTGTCCTGGGTACAGGAGTTTTATTGAGCGCGTGTGGAAA
TTCTAGCACTGCATCAAAAACCTATAACTATGTTTATTCAAGTGATCCATCTAGTTTGAACTATCTAGCAGAAAACCGCG
CAGCAACATCCGATATTGTTGCAAATTTGGTAGACGGGTTATTAGAAAATGACCAATATGGGAATATTATTCCATCATTA
GCAGAGGATTGGACTGTTTCTCAGGACGGTTTGACCTATACCTACAAACTTCGTAAGGATGCCAAGTGGTTTACTTCTGA
GGGAGAAGAATATGCGCCTGTAACTGCCCAGGATTTTGTGACAGGTTTGCAATATGCAGCTGATAAAAAATCAGAAGCTT
TGTATCTAGTGCAGGACTCTGTTGCTGGTTTGGATGACTATATCACTGGTAAAACAAGCGACTTTTCAACTGTCGGTGTC
AAGGCACTTGATGACCAAACGGTTCAATATACTTTGGTTAAACCAGAACTTTACTGGAATTCAAAAACACTTGCAACGAT
ACTTTTTCCTGTTAATGCAGATTTCCTGAAATCAAAAGGGGATGATTTTGGGAAGGCGGATCCATCTAGTATTTTGTACA
ATGGACCTTTCTTGATGAAAGCACTTGTCTCAAAATCTGCTATTGAATATAAGAAAAACCCTAATTACTGGGATGCTAAG
AATGTCTTTGTAGACGATGTGAAATTGACCTACTATGATGGTAGCGACCAAGAATCACTGGAACGTAATTTTACAGCTGG
TGCTTATACTACGGCTCGTCTTTTTCCTAACAGCTCCAGCTATGAAGGGATTAAAGAAAAATACAAAAACAATATCATCT
ATAGTATGCAAAATTCAACTTCATATTTCTTTAATTTTAACCTAGATAGGAAGTCTTACAATTATACTTCTAAAACAAGT
GACATTGAAAAGAAATCGACTCAGGAAGCAGTTCTCAATAAAAACTTCCGTCAGGCTATCAATTTTGCTTTTGACAGAAC
ATCTTATGGGGCTCAGTCTGAAGGGAAAGAAGGTGCAACAAAGATTTTGCGTAACCTAGTGGTTCCTCCAAACTTTGTCA
GTATCAAGGGAAAAGACTTTGGTGAAGTTGTAGCCTCTAAGATGGTCAACTATGGTAAGGAATGGCAAGGTATCAACTTT
GCGGATGGTCAAGACCCTTACTACAATCCTGAGAAAGCCAAGGCTAAGTTTGCGGAAGCTAAGAAAGAACTCGAAGCAAA
GGGTGTTCAATTCCCAATCCACTTGGATAAGACTGTGGAAGTAACAGATAAAGTAGGCATACAAGGAGTTAGTTCTATCA
AACAATCAATTGAATCTGTTTTAGGTTCTGATAATGTAGTGATTGACATTCAGCAATTAACATCAGATGAGTTTGACAGT
TCAGGCTACTTTGCTCAAACAGCTGCTCAGAAAGATTATGATTTATATCATGGCGGTTGGGGACCTGATTATCAAGACCC
GTCAACCTATCTCGATATTTTTAATACTAATAGTGGAGGATTTCTGCAAAATCTTGGACTAGAGCCTGGTGAGGCCAATG
ACAAGGCTAAGGCAGTTGGACTGGATGTCTATACTCAAATGTTGGAAGAAGCTAATAAAGAGCAAGATCCAGCCAAACGT
TATGAGAAATATGCTGATATTCAAGCTTGGTTGATTGATAGTTCTTTAGTTCTTCCAAGTGTTTCGCGTGGGGGAACACC
ATCATTGAGAAGAACCGTACCATTTGCTGCTGCCTATGGTTTAACCGGTACAAAAGGGGTTGAATCATATAAATACCTCA
AAGTACAAGATAAGATTGTCACAACAGACGAATATGCAAAAGCCAGAGAAAAATGGTTGAAAGAAAAAGAAGAATCCAAT
AAAAAAGCCCAAGAAGAATTGGCAAAACATGTCAAATAA

Domains

Predicted by InterProScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(76-519)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0A4G0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

56.422

100

0.566
  amiA3 Streptococcus thermophilus LMD-9

55.878

100

0.561
  amiA3 Streptococcus thermophilus LMG 18311

55.725

100

0.56

Multiple sequence alignment