Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NO473_RS14450 Genome accession   NZ_CP101666
Coordinates   2967833..2968423 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain M171-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2962833..2973423
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NO473_RS14415 yidF 2962948..2963445 (+) 498 WP_000148061.1 radical SAM protein -
  NO473_RS14420 emrD 2963453..2964637 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  NO473_RS14425 ysdE 2964719..2964793 (+) 75 WP_211180519.1 protein YsdE -
  NO473_RS14430 tisB 2964917..2965006 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  NO473_RS14435 ivbL 2965571..2965669 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  NO473_RS14440 ilvB 2965775..2967463 (+) 1689 WP_000168475.1 acetolactate synthase large subunit -
  NO473_RS14445 ilvN 2967467..2967757 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  NO473_RS14450 letA 2967833..2968423 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  NO473_RS14455 uhpB 2968423..2969925 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  NO473_RS14460 uhpC 2969935..2971254 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  NO473_RS14465 uhpT 2971392..2972783 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=611571 NO473_RS14450 WP_000633668.1 2967833..2968423(+) (letA) [Escherichia coli strain M171-1]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=611571 NO473_RS14450 WP_000633668.1 2967833..2968423(+) (letA) [Escherichia coli strain M171-1]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378