Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LE189_RS09305 Genome accession   NZ_CP084444
Coordinates   1952128..1952757 (+) Length   209 a.a.
NCBI ID   WP_002461333.1    Uniprot ID   -
Organism   Staphylococcus lugdunensis strain RMLUG6     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1947128..1957757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LE189_RS09280 (LE189_09275) - 1947880..1948860 (-) 981 WP_002492696.1 FUSC family protein -
  LE189_RS09285 (LE189_09280) map 1949105..1949860 (+) 756 WP_002461338.1 type I methionyl aminopeptidase -
  LE189_RS09290 (LE189_09285) - 1949986..1950372 (+) 387 WP_002477960.1 hypothetical protein -
  LE189_RS09295 (LE189_09290) liaF 1950397..1951098 (+) 702 WP_002461335.1 cell wall-active antibiotics response protein LiaF -
  LE189_RS09300 (LE189_09295) vraS 1951095..1952138 (+) 1044 WP_002461334.1 sensor histidine kinase Regulator
  LE189_RS09305 (LE189_09300) vraR 1952128..1952757 (+) 630 WP_002461333.1 two-component system response regulator VraR Regulator
  LE189_RS09310 (LE189_09305) - 1952930..1954159 (-) 1230 WP_002492699.1 YihY/virulence factor BrkB family protein -
  LE189_RS09315 (LE189_09310) - 1954362..1954646 (-) 285 WP_002461330.1 YtxH domain-containing protein -
  LE189_RS09320 (LE189_09315) - 1954653..1955117 (-) 465 WP_002492719.1 low molecular weight protein-tyrosine-phosphatase -
  LE189_RS09325 (LE189_09320) - 1955281..1955466 (+) 186 WP_002492715.1 DUF1128 domain-containing protein -
  LE189_RS09330 (LE189_09325) - 1955536..1956717 (+) 1182 WP_207754594.1 aminopeptidase -
  LE189_RS09335 (LE189_09330) - 1956751..1957278 (+) 528 WP_002461325.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23658.47 Da        Isoelectric Point: 5.3841

>NTDB_id=611379 LE189_RS09305 WP_002461333.1 1952128..1952757(+) (vraR) [Staphylococcus lugdunensis strain RMLUG6]
MTIKVLFVDDHEMVRIGISSYLSTQPDLEVVGEGASGKEAIAKAQELKPDLILMDLLMEDMDGVEATTQIKKEMPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIAEAVRKTYHGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=611379 LE189_RS09305 WP_002461333.1 1952128..1952757(+) (vraR) [Staphylococcus lugdunensis strain RMLUG6]
ATGACAATTAAAGTACTATTTGTAGATGACCATGAAATGGTAAGAATAGGAATTTCTAGTTATTTATCTACTCAACCAGA
CCTTGAAGTTGTAGGTGAAGGTGCTTCTGGTAAAGAGGCAATAGCTAAAGCACAAGAATTAAAGCCAGATTTAATCTTGA
TGGATTTATTAATGGAAGACATGGATGGCGTCGAAGCGACAACACAAATCAAGAAAGAGATGCCTCATATTAAAGTTGTA
ATGCTGACTAGCTTTATTGAGGATAAAGAAGTATATAGAGCGTTAGACGCTGGTGTTGACAGCTATATTTTAAAAACAAC
AAGCGCTAAAGATATCGCTGAAGCAGTGCGCAAAACATATCATGGAGAATCTGTATTTGAACCGGAAGTTCTGGTAAAAA
TGCGAAATAGAATGAAAAAACGTGCAGAGCTATATGAAATGTTAACAGAACGAGAAATGGAAATTTTACTGTTAATTGCT
AAAGGATATTCTAATCAAGAAATCGCAAGCGCATCACACATTACTATTAAAACAGTTAAAACACATGTGAGTAATATTTT
AAGCAAATTAGAAGTACAAGACCGTACACAAGCAGTAATCTATGCATTTCAGCATAATCTTATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383