Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LE164_RS11255 Genome accession   NZ_CP084440
Coordinates   2382262..2382891 (-) Length   209 a.a.
NCBI ID   WP_002461333.1    Uniprot ID   -
Organism   Staphylococcus lugdunensis strain RMLUG4     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2377262..2387891
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LE164_RS11225 (LE164_11240) - 2377741..2378268 (-) 528 WP_002461325.1 acyl-CoA thioesterase -
  LE164_RS11230 (LE164_11245) - 2378302..2379540 (-) 1239 WP_002477963.1 aminopeptidase -
  LE164_RS11235 (LE164_11250) - 2379553..2379738 (-) 186 WP_002492715.1 DUF1128 domain-containing protein -
  LE164_RS11240 (LE164_11255) - 2379902..2380366 (+) 465 WP_002477961.1 low molecular weight protein-tyrosine-phosphatase -
  LE164_RS11245 (LE164_11260) - 2380373..2380657 (+) 285 WP_002461330.1 YtxH domain-containing protein -
  LE164_RS11250 (LE164_11265) - 2380860..2382089 (+) 1230 WP_002461332.1 YihY/virulence factor BrkB family protein -
  LE164_RS11255 (LE164_11270) vraR 2382262..2382891 (-) 630 WP_002461333.1 two-component system response regulator VraR Regulator
  LE164_RS11260 (LE164_11275) vraS 2382881..2383924 (-) 1044 WP_002461334.1 sensor histidine kinase Regulator
  LE164_RS11265 (LE164_11280) liaF 2383921..2384622 (-) 702 WP_002461335.1 cell wall-active antibiotics response protein LiaF -
  LE164_RS11270 (LE164_11285) - 2384647..2385033 (-) 387 WP_002477960.1 hypothetical protein -
  LE164_RS11275 (LE164_11290) map 2385159..2385914 (-) 756 WP_002461338.1 type I methionyl aminopeptidase -
  LE164_RS11280 (LE164_11295) - 2386159..2387139 (+) 981 WP_002477959.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23658.47 Da        Isoelectric Point: 5.3841

>NTDB_id=611321 LE164_RS11255 WP_002461333.1 2382262..2382891(-) (vraR) [Staphylococcus lugdunensis strain RMLUG4]
MTIKVLFVDDHEMVRIGISSYLSTQPDLEVVGEGASGKEAIAKAQELKPDLILMDLLMEDMDGVEATTQIKKEMPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIAEAVRKTYHGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=611321 LE164_RS11255 WP_002461333.1 2382262..2382891(-) (vraR) [Staphylococcus lugdunensis strain RMLUG4]
ATGACAATTAAAGTACTATTTGTAGATGACCATGAAATGGTAAGAATAGGAATTTCTAGTTATTTATCTACTCAGCCAGA
CCTTGAAGTTGTAGGTGAAGGTGCTTCTGGTAAAGAGGCAATAGCTAAAGCACAAGAATTAAAGCCAGATTTAATCTTGA
TGGATTTATTAATGGAAGACATGGATGGCGTCGAAGCGACAACGCAAATCAAGAAAGAGATGCCTCATATTAAAGTTGTA
ATGCTGACTAGCTTTATTGAGGATAAAGAAGTATATAGAGCGTTAGACGCTGGTGTTGACAGCTATATTTTAAAAACAAC
AAGCGCTAAAGATATCGCTGAAGCAGTGCGCAAAACATATCATGGAGAATCTGTATTTGAACCGGAAGTTCTGGTAAAAA
TGCGAAATAGAATGAAAAAACGTGCAGAGCTATATGAAATGTTAACAGAACGAGAAATGGAAATTTTACTGTTAATTGCT
AAAGGATATTCTAATCAAGAAATCGCAAGCGCATCACACATTACTATTAAAACAGTTAAAACACATGTGAGTAATATTTT
AAGCAAATTAGAAGTACAAGACCGTACACAAGCAGTAATCTATGCATTTCAGCACAATCTTATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383