Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RES5_RS04625 Genome accession   NZ_CP084235
Coordinates   934886..935515 (+) Length   209 a.a.
NCBI ID   WP_161510947.1    Uniprot ID   -
Organism   Staphylococcus haemolyticus strain SE2.14     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 929886..940515
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RES5_RS04600 (RES5_004600) - 930594..931403 (-) 810 Protein_912 SDR family oxidoreductase -
  RES5_RS04605 (RES5_004605) - 931523..932482 (-) 960 Protein_913 HoxN/HupN/NixA family nickel/cobalt transporter -
  RES5_RS04610 (RES5_004610) - 932741..933127 (+) 387 WP_161510945.1 hypothetical protein -
  RES5_RS04615 (RES5_004615) liaF 933152..933853 (+) 702 WP_011275374.1 cell wall-active antibiotics response protein LiaF -
  RES5_RS04620 (RES5_004620) vraS 933850..934896 (+) 1047 WP_161510946.1 sensor histidine kinase Regulator
  RES5_RS04625 (RES5_004625) vraR 934886..935515 (+) 630 WP_161510947.1 two-component system response regulator VraR Regulator
  RES5_RS04630 (RES5_004630) - 935578..936789 (-) 1212 WP_053026912.1 YihY/virulence factor BrkB family protein -
  RES5_RS04635 (RES5_004635) - 936988..937272 (-) 285 WP_037551134.1 YtxH domain-containing protein -
  RES5_RS04640 (RES5_004640) - 937278..937742 (-) 465 WP_161517177.1 low molecular weight protein-tyrosine-phosphatase -
  RES5_RS04645 (RES5_004645) - 937884..938093 (+) 210 WP_076689932.1 DUF1128 domain-containing protein -
  RES5_RS04650 (RES5_004650) - 938107..939354 (+) 1248 WP_037551132.1 aminopeptidase -
  RES5_RS04655 (RES5_004655) - 939387..939920 (+) 534 WP_070582094.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23621.26 Da        Isoelectric Point: 5.0058

>NTDB_id=610225 RES5_RS04625 WP_161510947.1 934886..935515(+) (vraR) [Staphylococcus haemolyticus strain SE2.14]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEIVGEGESGKDAITKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIADAVRKTYNGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=610225 RES5_RS04625 WP_161510947.1 934886..935515(+) (vraR) [Staphylococcus haemolyticus strain SE2.14]
ATGACGATTAAAGTATTGTTCGTTGATGACCATGAAATGGTTAGAATTGGGATATCAAGTTATCTATCAACACAATCTGA
CATTGAGATAGTTGGAGAAGGGGAATCTGGTAAAGATGCCATTACAAAAGCTCATGAATTAAAACCTGATTTAATTCTTA
TGGATTTATTAATGGATGACATGGATGGCGTTGAAGCAACTACTCAAATCAAAAAAGATTTGCCACATATTAAAGTTGTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATAGAGCATTAGATGCTGGTGTAGATAGCTATATTTTAAAAACGAC
TAGTGCTAGTGATATAGCCGACGCAGTACGCAAAACTTATAATGGTGAATCTGTATTTGAACCTGAAGTTTTAGTTAAGA
TGCGTAATAGAATGAAGAAACGTGCAGAATTATATGAAATGCTGACTGAGCGTGAAATGGAAATTTTATTATTAATTGCA
AAAGGGTATTCAAATCAAGAAATAGCGAGTGCTTCTCATATTACAATTAAAACCGTTAAAACTCATGTAAGTAATATATT
GAGTAAATTAGAAGTACAAGATAGAACACAAGCCGTAATTTATGCATTCCAACATAATTTGATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364