Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NML17_RS22515 Genome accession   NZ_CP101274
Coordinates   4621276..4621866 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain EC21Z-014     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4616276..4626866
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NML17_RS22500 (NML17_22505) uhpT 4616916..4618307 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  NML17_RS22505 (NML17_22510) uhpC 4618445..4619764 (-) 1320 WP_001296914.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  NML17_RS22510 (NML17_22515) uhpB 4619774..4621276 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  NML17_RS22515 (NML17_22520) letA 4621276..4621866 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  NML17_RS22520 (NML17_22525) ilvN 4621941..4622231 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  NML17_RS22525 (NML17_22530) ilvB 4622235..4623923 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  NML17_RS22530 (NML17_22535) ivbL 4624029..4624127 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  NML17_RS22535 (NML17_22540) tisB 4624692..4624781 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  NML17_RS22540 (NML17_22545) ysdE 4625044..4625118 (-) 75 WP_211180519.1 protein YsdE -
  NML17_RS22545 (NML17_22550) emrD 4625200..4626384 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=609918 NML17_RS22515 WP_000633668.1 4621276..4621866(-) (letA) [Escherichia coli strain EC21Z-014]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=609918 NML17_RS22515 WP_000633668.1 4621276..4621866(-) (letA) [Escherichia coli strain EC21Z-014]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378