Detailed information NTG0060990

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: EL277_RS06095
• Genome accession: NZ_AP018936
• Coordinates: 1164270..1166258 (-)
• Length: 662 a.a.
• NCBI ID: WP_000607027.1
• Uniprot ID: Q54986
• Organism: Streptococcus pneumoniae strain NU83127
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1159270..1171258

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL277_RS06055 (SPNU_1152)	coaB	1159575..1160264 (+)	690	WP_000699501.1	phosphopantothenate--cysteine ligase	-
EL277_RS06060 (SPNU_1153)	coaC	1160276..1160827 (+)	552	WP_001284128.1	phosphopantothenoylcysteine decarboxylase	-
EL277_RS06065 (SPNU_1154)	-	1160811..1161374 (+)	564	WP_000747408.1	ECF transporter S component	-
EL277_RS06070 (SPNU_1155)	-	1161656..1162183 (+)	528	WP_001827349.1	ECF transporter S component	-
EL277_RS06075 (SPNU_1156)	-	1162195..1162710 (+)	516	WP_000159169.1	transcription repressor NadR	-
EL277_RS06080 (SPNU_1157)	-	1162707..1163174 (-)	468	WP_000091551.1	8-oxo-dGTP diphosphatase	-
EL277_RS06085 (SPNU_1158)	-	1163243..1163731 (-)	489	WP_000216002.1	GNAT family N-acetyltransferase	-
EL277_RS06090 (SPNU_1159)	-	1163697..1164260 (-)	564	WP_000639829.1	GNAT family N-acetyltransferase	-
EL277_RS06095 (SPNU_1160)	uvrB	1164270..1166258 (-)	1989	WP_000607027.1	excinuclease ABC subunit UvrB	Machinery gene
EL277_RS06100 (SPNU_1161)	-	1166335..1167288 (-)	954	WP_000792117.1	CPBP family intramembrane glutamic endopeptidase	-
EL277_RS06105 (SPNU_1162)	-	1167458..1169623 (+)	2166	WP_000726272.1	ABC transporter substrate-binding protein/permease	-
EL277_RS06110 (SPNU_1163)	-	1169623..1170363 (+)	741	WP_001096313.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 662 a.a.
• Molecular weight: 75733.76 Da
• Isoelectric Point: 4.5848

>NTDB_id=60990 EL277_RS06095 WP_000607027.1 1164270..1166258(-) (uvrB) [Streptococcus pneumoniae strain NU83127]
MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKALD

Nucleotide

• Length: 1989 bp

>NTDB_id=60990 EL277_RS06095 WP_000607027.1 1164270..1166258(-) (uvrB) [Streptococcus pneumoniae strain NU83127]
ATGATCAATCACATTACAGATAATCAATTTAAACTAGTATCAAAATATCAACCATCAGGAGATCAACCCCAAGCTATCGA
GCAGTTGGTGGATAACATTGAGGGGGGAGAAAAAGCTCAGATTCTGATGGGGGCGACTGGAACAGGGAAGACCTATACTA
TGAGTCAGGTCATTTCTAAAGTCAATAAACCAACTCTGGTTATTGCCCACAATAAAACTCTGGCTGGTCAGCTCTATGGG
GAGTTTAAGGAATTTTTCCCTGAAAATGCAGTTGAGTATTTCGTATCCTACTATGATTATTACCAGCCAGAGGCCTATGT
CCCTTCTAGCGATACCTATATTGAGAAGGATAGTTCTGTCAATGACGAGATTGACAAGCTTCGCCACTCAGCTACCTCAG
CCCTTTTGGAGCGTAATGATGTTATTGTCGTGGCCTCAGTCTCTTGTATCTATGGTTTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCTGGTCTAGAGATTTCTCGTGATAAACTCTTGAATGACTTGGTCGATATTCAGTTTGA
ACGTAATGATATTGATTTCCAACGCGGAAGATTTCGCGTTCGTGGGGATGTGGTAGAGATTTTCCCAGCTTCCCGAGATG
AACATGCCTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATTCGTGAAGTTGAGGCTCTGACAGGTCAGGTGTTG
GGAGAAGTGGATCATTTAGCGATTTTCCCAGCGACACACTTTGTGACCAATGACGACCACATGGAAGTTGCCATTGCAAA
GATTCAGGCCGAGTTGGAAGAACAATTAGCTGTCTTTGAAAAGGAAGGTAAACTGCTTGAAGCCCAGCGTTTGAAACAGC
GGACAGAGTATGATATCGAAATGTTGCGTGAGATGGGCTATACCAATGGGGTTGAAAATTATTCTCGCCACATGGATGGA
CGGAGCGAAGGAGAGCCTCCTTATACGCTTCTCGACTTCTTCCCAGATGATTTCTTGATTATGATTGACGAGAGTCATAT
GACCATAGGGCAAATCAAGGGCATGTACAATGGAGACCGTTCGCGTAAAGAAATGCTGGTTAATTATGGTTTCCGTTTGC
CGTCTGCTTTGGACAATCGTCCTCTCCGTCGGGAGGAGTTTGAGAGTCACGTTCATCAGATTGTTTACGTTTCAGCGACA
CCTGGTGACTATGAAAATGAACAGACCGAGACAGTGATTGAGCAAATCATTCGTCCAACGGGACTCTTGGATCCAGAGGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGACCTCTTGGGTGAAATCAATGCCCGCGTTGAAAAAAATGAGCGTACCT
TTATCACAACTTTGACCAAGAAAATGGCAGAGGATTTGACCGACTACTTCAAGGAAATGGGTATCAAGGTCAAGTACATG
CACTCGGATATCAAGACCTTGGAACGGACGGAGATTATCCGTGACCTGCGCTTGGGTGTCTTTGATGTCTTGGTCGGAAT
TAACCTGCTCCGTGAAGGAATTGACGTTCCTGAAGTGAGCCTCGTAGCTATTCTCGATGCTGACAAGGAAGGTTTCCTTC
GCAACGAACGTGGACTCATCCAGACCATTGGACGTGCTGCACGTAATAGCGAAGGTCATGTTATCATGTATGCGGACACG
GTTACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGCAAAATCCAGATGGCCTATAATGAAGAACATGG
TATCGTTCCACAAACCATCAAGAAAGAAATCCGTGACTTGATTGCTGTGACCAAGGCAGTTGCTAAGGAAGAAGACAAGG
AAGTCGATATCAATAGCCTCAACAAACAAGAGCGCAAAGAACTAGTCAAAAAGCTTGAGAAACAAATGCAAGAAGCAGTT
GAAGTGCTTGACTTTGAACTAGCAGCTCAGATTCGTGATATGATGCTGGAAGTCAAGGCCTTGGATTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• UvrB/uvrC motif (UVR) (626-660)

• Helicase conserved C-terminal domain (Helicase_C) (443-549)

• Type III restriction enzyme, res subunit (ResIII) (17-143)

• UvrB interaction domain (UvrB_inter) (164-254)

3D structure

• AlphaFold DB: Q54986

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae TIGR4	100	100	1
uvrB	Streptococcus pneumoniae R6	99.849	100	0.998
uvrB	Streptococcus pneumoniae D39	99.849	100	0.998