Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   M6G08_RS10360 Genome accession   NZ_CP101137
Coordinates   2285387..2286511 (-) Length   374 a.a.
NCBI ID   WP_217248019.1    Uniprot ID   -
Organism   Streptomyces sp. M92     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2280387..2291511
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M6G08_RS10340 (M6G08_10345) - 2281232..2283025 (+) 1794 WP_272586874.1 sensor histidine kinase -
  M6G08_RS10345 (M6G08_10350) vraR 2283022..2283687 (+) 666 WP_272586875.1 response regulator transcription factor Regulator
  M6G08_RS10350 (M6G08_10355) - 2283694..2284335 (-) 642 WP_272586876.1 phosphatase PAP2 family protein -
  M6G08_RS10355 (M6G08_10360) - 2284510..2285355 (+) 846 WP_272586877.1 hypothetical protein -
  M6G08_RS10360 (M6G08_10365) disA 2285387..2286511 (-) 1125 WP_217248019.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  M6G08_RS10365 (M6G08_10370) radA/sms 2286593..2288002 (-) 1410 WP_272586878.1 DNA repair protein RadA Machinery gene
  M6G08_RS10370 (M6G08_10375) - 2289030..2290880 (+) 1851 WP_272586879.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40113.92 Da        Isoelectric Point: 5.0058

>NTDB_id=609001 M6G08_RS10360 WP_217248019.1 2285387..2286511(-) (disA) [Streptomyces sp. M92]
MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTLLRDGLERVLRGNTGGLMVLGSDKTVESMCTGGFVLDVEFTPTRLR
ELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=609001 M6G08_RS10360 WP_217248019.1 2285387..2286511(-) (disA) [Streptomyces sp. M92]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTGCCGATGGCCTGATGCGCGCCTCGCT
GAGCGCGGTGGCGCCCGGCACGCTGCTGCGGGACGGCCTGGAGCGGGTCCTGCGCGGCAACACCGGCGGCCTGATGGTGC
TGGGCTCGGACAAGACCGTCGAGTCCATGTGCACCGGCGGTTTCGTCCTGGATGTGGAGTTCACTCCGACGCGGCTGCGG
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTGTCGTCGGACCTGTCGAAGATCCTGCGGGCGGGGGTGCAGCTGCTTCC
GGACCCGACCATTCCGACGGAGGAGACCGGTACCCGGCACCGTACGGCGGACCGGGTGAGCAAGCAGGTCGGGTTCCCCG
TCGTCTCGGTCTCGCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGCAGCGGCGGGTGCTCGAGGATTCCGCCGCC
ATCCTGTCGCGGGCCAATCAGGCGCTGGCGACCCTGGAGCGGTACAAGCTGCGGCTGGACGAGGTCGCGGGCACCCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACCGTCCGGGACGTCTCGGCGGTCGCGCAGCGGCTGGAGATGGTGCGCCGGATCG
CGACCGAGATCGCCGAGTACGTGGTCGAGCTGGGGACGGACGGGCGCCTCCTGGCGCTTCAGCTGGACGAGTTGATCGCC
GGTGTCGAGCCGGAGCGGGAGCTGGTCGTGCGGGACTACGTGCCCGAGCCGACCGCGAAGCGGTCCCGCACGGTCGACGA
GGCGCTCGCCGAGCTGGACAAGCTCAGCCATGCGGAGCTGCTCGAACTATCGACGGTGGCGCGGGCGTTGGGGTACACGG
GCTCGCCCGAGACGCTGGACTCCGCGGTGTCGCCGCGCGGGTTCCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGGGCGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGTCTGCAGAAGCTGCTCGCCGCGAGCGTGGACGACCTGCAGACGGTGGA
CGGCGTCGGTGAGGCGCGGGCGCGCAGCGTGCGGGAAGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTCGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

46.26

96.524

0.447