Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   M6G08_RS10345 Genome accession   NZ_CP101137
Coordinates   2283022..2283687 (+) Length   221 a.a.
NCBI ID   WP_272586875.1    Uniprot ID   -
Organism   Streptomyces sp. M92     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2278022..2288687
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M6G08_RS10325 (M6G08_10325) - 2278469..2279134 (-) 666 WP_272586872.1 hypothetical protein -
  M6G08_RS10330 (M6G08_10330) - 2279122..2279655 (-) 534 WP_043371941.1 SigE family RNA polymerase sigma factor -
  M6G08_RS10335 (M6G08_10335) - 2279857..2280804 (-) 948 WP_272586873.1 A/G-specific adenine glycosylase -
  M6G08_RS10340 (M6G08_10345) - 2281232..2283025 (+) 1794 WP_272586874.1 sensor histidine kinase -
  M6G08_RS10345 (M6G08_10350) vraR 2283022..2283687 (+) 666 WP_272586875.1 response regulator transcription factor Regulator
  M6G08_RS10350 (M6G08_10355) - 2283694..2284335 (-) 642 WP_272586876.1 phosphatase PAP2 family protein -
  M6G08_RS10355 (M6G08_10360) - 2284510..2285355 (+) 846 WP_272586877.1 hypothetical protein -
  M6G08_RS10360 (M6G08_10365) disA 2285387..2286511 (-) 1125 WP_217248019.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  M6G08_RS10365 (M6G08_10370) radA/sms 2286593..2288002 (-) 1410 WP_272586878.1 DNA repair protein RadA Machinery gene

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23250.69 Da        Isoelectric Point: 5.4545

>NTDB_id=609000 M6G08_RS10345 WP_272586875.1 2283022..2283687(+) (vraR) [Streptomyces sp. M92]
MIRVLLADDEAMVRAGVRAILASGGESEVVAEAGDGREAVELARAHRPDVALLDIRMPRLDGLAAAEEIARTVPGTAVAM
LTTFSEQSYVARALAAGATGFLLKSGDPYELMAGVRAVAEGAAFLSPKVARYVVEDLGRDGGRLAREERARASVARLSPR
EREVLGLVGAGLSNPEIAARLHLVEGTVKAYVSAVLDRLEVRNRVRAAIVAYEAGLVAPEA

Nucleotide


Download         Length: 666 bp        

>NTDB_id=609000 M6G08_RS10345 WP_272586875.1 2283022..2283687(+) (vraR) [Streptomyces sp. M92]
GTGATCCGGGTACTGCTGGCCGACGACGAGGCGATGGTGCGGGCCGGCGTGCGCGCCATCCTGGCGAGCGGCGGCGAGAG
CGAGGTCGTCGCCGAGGCGGGCGACGGCCGCGAGGCGGTCGAACTCGCCCGCGCCCACCGCCCCGACGTGGCCCTGCTGG
ACATCCGCATGCCCCGCCTGGACGGCCTCGCGGCGGCCGAGGAGATCGCCCGGACCGTCCCCGGCACGGCCGTCGCGATG
CTGACCACGTTCTCCGAACAGTCCTACGTGGCCCGCGCCCTGGCCGCCGGAGCCACCGGCTTCCTGCTCAAGTCCGGCGA
CCCCTACGAACTGATGGCCGGCGTGCGGGCCGTGGCGGAGGGCGCGGCCTTCCTGTCCCCGAAGGTCGCCCGTTACGTCG
TCGAGGACCTCGGCCGGGACGGCGGCCGCCTCGCCCGCGAGGAACGGGCTCGCGCGAGCGTCGCCCGCCTCAGCCCGCGC
GAGCGCGAGGTCCTCGGCCTCGTCGGCGCCGGCCTGTCCAACCCGGAGATCGCCGCCCGGCTGCACCTCGTCGAGGGCAC
GGTGAAGGCGTACGTGAGCGCGGTCCTGGACCGGCTGGAGGTACGCAACCGGGTCCGGGCGGCGATCGTCGCGTACGAGG
CGGGACTGGTCGCGCCGGAAGCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-114)

Bacterial regulatory proteins, luxR family (GerE)

(157-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.53

99.095

0.362