Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NMD30_RS00185 Genome accession   NZ_CP100994
Coordinates   31161..31751 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain ET201     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 26161..36751
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD30_RS00150 (NMD30_00145) yidF 26276..26773 (+) 498 WP_000148064.1 radical SAM protein -
  NMD30_RS00155 (NMD30_00150) emrD 26781..27965 (-) 1185 WP_001306726.1 multidrug efflux MFS transporter EmrD -
  NMD30_RS00160 (NMD30_00155) ysdE 28047..28121 (+) 75 WP_211180519.1 protein YsdE -
  NMD30_RS00165 (NMD30_00160) tisB 28245..28334 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  NMD30_RS00170 (NMD30_00165) ivbL 28899..28997 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  NMD30_RS00175 (NMD30_00170) ilvB 29103..30791 (+) 1689 WP_370612613.1 acetolactate synthase large subunit -
  NMD30_RS00180 (NMD30_00175) ilvN 30795..31085 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  NMD30_RS00185 (NMD30_00180) letA 31161..31751 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  NMD30_RS00190 (NMD30_00185) uhpB 31751..33253 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  NMD30_RS00195 (NMD30_00190) uhpC 33263..34582 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  NMD30_RS00200 (NMD30_00195) uhpT 34720..36111 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=608310 NMD30_RS00185 WP_000633668.1 31161..31751(+) (letA) [Escherichia coli strain ET201]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=608310 NMD30_RS00185 WP_000633668.1 31161..31751(+) (letA) [Escherichia coli strain ET201]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378