Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NMD31_RS10230 Genome accession   NZ_CP100987
Coordinates   2102075..2102731 (+) Length   218 a.a.
NCBI ID   WP_000611338.1    Uniprot ID   -
Organism   Escherichia coli strain ET210     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2097075..2107731
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD31_RS10195 (NMD31_10160) dcyD 2097954..2098940 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  NMD31_RS10200 (NMD31_10165) tcyL 2098955..2099623 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NMD31_RS10205 (NMD31_10170) tcyN 2099620..2100372 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NMD31_RS10210 (NMD31_10175) sdiA 2100602..2101324 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  NMD31_RS10215 (NMD31_10180) yecF 2101392..2101616 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NMD31_RS10220 (NMD31_10185) yecU 2101603..2101779 (-) 177 WP_001302050.1 protein YecU -
  NMD31_RS10225 - 2101817..2101933 (-) 117 WP_001302039.1 hypothetical protein -
  NMD31_RS10230 (NMD31_10190) letA 2102075..2102731 (+) 657 WP_000611338.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NMD31_RS10235 (NMD31_10195) uvrC 2102728..2104560 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NMD31_RS10240 (NMD31_10200) pgsA 2104617..2105165 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NMD31_RS10260 (NMD31_10220) yecA 2105815..2106480 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23908.65 Da        Isoelectric Point: 6.9614

>NTDB_id=608266 NMD31_RS10230 WP_000611338.1 2102075..2102731(+) (letA) [Escherichia coli strain ET210]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNSVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=608266 NMD31_RS10230 WP_000611338.1 2102075..2102731(+) (letA) [Escherichia coli strain ET210]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGCGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATTCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGCAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGTGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAGCAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.691

94.954

0.491
  letA Legionella pneumophila strain ERS1305867

51.691

94.954

0.491