Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NMD37_RS00180 Genome accession   NZ_CP100966
Coordinates   33568..34158 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain ET350     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 28568..39158
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD37_RS00165 (NMD37_00160) ilvN 29842..30132 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  NMD37_RS00170 (NMD37_00165) - 30395..31696 (+) 1302 WP_370598566.1 hypothetical protein -
  NMD37_RS00175 (NMD37_00170) - 32304..33407 (+) 1104 WP_133302650.1 hypothetical protein -
  NMD37_RS00180 (NMD37_00175) letA 33568..34158 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  NMD37_RS00185 (NMD37_00180) uhpB 34158..35660 (+) 1503 WP_087900868.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  NMD37_RS00190 (NMD37_00185) uhpC 35670..36989 (+) 1320 WP_000936560.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  NMD37_RS00195 (NMD37_00190) uhpT 37127..38518 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=607901 NMD37_RS00180 WP_000633668.1 33568..34158(+) (letA) [Escherichia coli strain ET350]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=607901 NMD37_RS00180 WP_000633668.1 33568..34158(+) (letA) [Escherichia coli strain ET350]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGTTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGTG
ATATCTCAATGCCGGATATATCTGGGCTGGAGCTGTTAAGCCAGCTACCGAAAGGTATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAACAGGCGCTTAACGCGGGGGCGCGCGGTTTTCTCTCTAAACGCTGTAGCCCGGACGA
GCTGATCGCTGCCGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACACCGGATATCGCTATTAAACTGGCATCCGGTC
GCCAGGACCCGCTGACCAAACGCGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378