Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NMD43_RS00185 Genome accession   NZ_CP100947
Coordinates   34328..34918 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain ET490     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 29328..39918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD43_RS00155 (NMD43_00150) ysdE 29890..29964 (+) 75 WP_211180519.1 protein YsdE -
  NMD43_RS00160 (NMD43_00155) tisB 30088..30177 (-) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  NMD43_RS00165 (NMD43_00160) - 30454..31674 (-) 1221 WP_000343760.1 ISL3-like element ISKox3 family transposase -
  NMD43_RS00170 (NMD43_00165) ivbL 32066..32164 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  NMD43_RS00175 (NMD43_00170) ilvB 32270..33958 (+) 1689 WP_000168475.1 acetolactate synthase large subunit -
  NMD43_RS00180 (NMD43_00175) ilvN 33962..34252 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  NMD43_RS00185 (NMD43_00180) letA 34328..34918 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  NMD43_RS00190 (NMD43_00185) uhpB 34918..36420 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  NMD43_RS00195 (NMD43_00190) uhpC 36430..37749 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  NMD43_RS00200 (NMD43_00195) uhpT 37887..39278 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=607495 NMD43_RS00185 WP_000633668.1 34328..34918(+) (letA) [Escherichia coli strain ET490]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=607495 NMD43_RS00185 WP_000633668.1 34328..34918(+) (letA) [Escherichia coli strain ET490]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378