Detailed information NTG0060728

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: JMUB1273_RS08720
• Genome accession: NZ_AP018922
• Coordinates: 1750692..1751681 (-)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus strain JMUB1273
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1745692..1756681

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMUB1273_RS08705 (JMUB1273_1623)	acsA	1746893..1748599 (-)	1707	WP_000862083.1	acetate--CoA ligase	-
JMUB1273_RS08710 (JMUB1273_1624)	-	1748768..1749400 (+)	633	WP_001015996.1	hypothetical protein	-
JMUB1273_RS08715 (JMUB1273_1625)	-	1749425..1750594 (+)	1170	WP_001184007.1	acetoin utilization protein AcuC	-
JMUB1273_RS08720 (JMUB1273_1626)	ccpA	1750692..1751681 (-)	990	WP_000219066.1	catabolite control protein A	Regulator
JMUB1273_RS08725	-	1751754..1751867 (-)	114	WP_001803513.1	hypothetical protein	-
JMUB1273_RS08730 (JMUB1273_1627)	-	1752221..1753312 (-)	1092	WP_000066378.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
JMUB1273_RS08735	-	1753773..1753856 (-)	84	WP_031789490.1	hypothetical protein	-
JMUB1273_RS08740 (JMUB1273_1628)	-	1754012..1755376 (-)	1365	WP_000193943.1	hypothetical protein	-
JMUB1273_RS08745 (JMUB1273_1629)	-	1755450..1755941 (-)	492	WP_000383814.1	DUF948 domain-containing protein	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=60728 JMUB1273_RS08720 WP_000219066.1 1750692..1751681(-) (ccpA) [Staphylococcus aureus strain JMUB1273]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=60728 JMUB1273_RS08720 WP_000219066.1 1750692..1751681(-) (ccpA) [Staphylococcus aureus strain JMUB1273]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAAGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGTCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGTAATCTTCCAGATGCTATA
TTATGTATCAGTGACGAAGAAGCTATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGTTTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462