Detailed information NTG0606814

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: LA346_RS03525
• Genome accession: NZ_CP083627
• Coordinates: 653720..654730 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain FDAARGOS_1508
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 648720..659730

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LA346_RS03500 (LA346_03500)	-	649885..650179 (-)	295	Protein_681	hypothetical protein	-
LA346_RS03505 (LA346_03505)	-	650341..650793 (+)	453	WP_000079148.1	universal stress protein	-
LA346_RS03510 (LA346_03510)	-	650828..652216 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
LA346_RS03515 (LA346_03515)	-	652282..653244 (+)	963	WP_001124786.1	asparaginase	-
LA346_RS03520 (LA346_03520)	-	653273..653656 (-)	384	WP_001092022.1	hypothetical protein	-
LA346_RS03525 (LA346_03525)	ccpA	653720..654730 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
LA346_RS03530 (LA346_03530)	-	655155..655754 (-)	600	WP_000866703.1	response regulator transcription factor	-
LA346_RS03535 (LA346_03535)	-	655755..656852 (-)	1098	WP_000893503.1	sensor histidine kinase	-
LA346_RS03540 (LA346_03540)	-	656852..657589 (-)	738	WP_000832916.1	ABC transporter permease	-
LA346_RS03545 (LA346_03545)	-	657591..658475 (-)	885	WP_000219359.1	ABC transporter ATP-binding protein	-
LA346_RS03550 (LA346_03550)	-	658462..658656 (-)	195	WP_000715302.1	hypothetical protein	-
LA346_RS03555 (LA346_03555)	-	658653..658859 (-)	207	Protein_692	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=606814 LA346_RS03525 WP_000990607.1 653720..654730(-) (ccpA) [Streptococcus pneumoniae strain FDAARGOS_1508]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=606814 LA346_RS03525 WP_000990607.1 653720..654730(-) (ccpA) [Streptococcus pneumoniae strain FDAARGOS_1508]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568