Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NMD57_RS09460 Genome accession   NZ_CP100895
Coordinates   1928638..1929294 (+) Length   218 a.a.
NCBI ID   WP_000611336.1    Uniprot ID   -
Organism   Escherichia coli strain ET846     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1923638..1934294
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD57_RS09415 (NMD57_09355) dcyD 1923740..1924726 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NMD57_RS09420 (NMD57_09360) tcyL 1924741..1925409 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NMD57_RS09425 (NMD57_09365) tcyN 1925406..1926158 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NMD57_RS09430 (NMD57_09370) sdiA 1926388..1926771 (+) 384 Protein_1842 transcriptional regulator SdiA -
  NMD57_RS09435 (NMD57_09375) - 1926828..1927525 (+) 698 WP_095033700.1 IS1-like element IS1B family transposase -
  NMD57_RS09440 (NMD57_09380) sdiA 1927540..1927887 (+) 348 Protein_1844 transcriptional regulator SdiA -
  NMD57_RS09445 (NMD57_09385) yecF 1927955..1928179 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NMD57_RS09450 (NMD57_09390) yecU 1928166..1928342 (-) 177 WP_000590344.1 protein YecU -
  NMD57_RS09455 - 1928380..1928496 (-) 117 Protein_1847 transcriptional regulator -
  NMD57_RS09460 (NMD57_09395) letA 1928638..1929294 (+) 657 WP_000611336.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NMD57_RS09465 (NMD57_09400) uvrC 1929291..1931123 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NMD57_RS09470 (NMD57_09405) pgsA 1931180..1931728 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NMD57_RS09490 (NMD57_09425) - 1932424..1933164 (-) 741 WP_105629615.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23878.58 Da        Isoelectric Point: 6.6397

>NTDB_id=606468 NMD57_RS09460 WP_000611336.1 1928638..1929294(+) (letA) [Escherichia coli strain ET846]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITNGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=606468 NMD57_RS09460 WP_000611336.1 1928638..1929294(+) (letA) [Escherichia coli strain ET846]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAATGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486