Detailed information NTG0605818

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: K9864_RS18510
• Genome accession: NZ_CP083436
• Coordinates: 3687040..3688203 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain HC-8
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3682040..3693203

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K9864_RS18480 (K9864_18365)	-	3682305..3682724 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
K9864_RS18485 (K9864_18370)	comFC	3682798..3683487 (-)	690	WP_197535984.1	ComF family protein	Machinery gene
K9864_RS18490 (K9864_18375)	-	3683493..3683777 (-)	285	WP_014419011.1	late competence development ComFB family protein	-
K9864_RS18495 (K9864_18380)	comFA	3683835..3685220 (-)	1386	WP_014419012.1	DEAD/DEAH box helicase	Machinery gene
K9864_RS18500 (K9864_18385)	-	3685328..3686176 (-)	849	WP_003151387.1	DegV family protein	-
K9864_RS18505 (K9864_18390)	degU	3686274..3686963 (-)	690	WP_111927758.1	two-component system response regulator DegU	Regulator
K9864_RS18510 (K9864_18395)	degS	3687040..3688203 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
K9864_RS18515 (K9864_18400)	-	3688426..3689073 (+)	648	WP_007614107.1	YigZ family protein	-
K9864_RS18520 (K9864_18405)	-	3689078..3690292 (+)	1215	WP_014419013.1	LCP family protein	-
K9864_RS18525 (K9864_18410)	-	3690382..3691458 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
K9864_RS18530 (K9864_18415)	tuaH	3691591..3692787 (-)	1197	WP_014419014.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=605818 K9864_RS18510 WP_007407484.1 3687040..3688203(-) (degS) [Bacillus velezensis strain HC-8]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=605818 K9864_RS18510 WP_007407484.1 3687040..3688203(-) (degS) [Bacillus velezensis strain HC-8]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951