NTDB

Overview

Name	ciaH	Type	Regulator
Locus tag	NLY75_RS04415	Genome accession	NZ_CP100432
Coordinates	864830..866209 (+)	Length	459 a.a.
NCBI ID	WP_024381361.1	Uniprot ID	-
Organism	Streptococcus suis T15
Function	repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 859830..871209

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NLY75_RS04385 (NLY75_04385)	pstA	860256..861143 (+)	888	WP_002937616.1	phosphate ABC transporter permease PstA	-
NLY75_RS04390 (NLY75_04390)	pstB	861168..861971 (+)	804	WP_002940866.1	phosphate ABC transporter ATP-binding protein PstB	-
NLY75_RS04395 (NLY75_04395)	pstB	861983..862741 (+)	759	WP_023369942.1	phosphate ABC transporter ATP-binding protein PstB	-
NLY75_RS04400 (NLY75_04400)	phoU	862770..863426 (+)	657	WP_002937611.1	phosphate signaling complex protein PhoU	-
NLY75_RS04405 (NLY75_04405)	-	863592..863972 (+)	381	WP_023369940.1	hypothetical protein	-
NLY75_RS04410 (NLY75_04410)	ciaR	864166..864837 (+)	672	WP_009909965.1	response regulator transcription factor	Regulator
NLY75_RS04415 (NLY75_04415)	ciaH	864830..866209 (+)	1380	WP_024381361.1	cell wall metabolism sensor histidine kinase WalK	Regulator
NLY75_RS04420 (NLY75_04420)	-	866533..867762 (+)	1230	WP_023369936.1	transglutaminase domain-containing protein	-
NLY75_RS04425 (NLY75_04425)	-	868045..868905 (-)	861	WP_194717471.1	IS3 family transposase	-
NLY75_RS04430 (NLY75_04430)	-	868929..869249 (-)	321	WP_023369020.1	transposase	-
NLY75_RS04435 (NLY75_04435)	rpsT	869338..869586 (-)	249	WP_012027069.1	30S ribosomal protein S20	-
NLY75_RS04440 (NLY75_04440)	coaA	869645..870565 (-)	921	WP_002935283.1	type I pantothenate kinase	-

Sequence

Protein

Download Length: 459 a.a. Molecular weight: 51961.70 Da Isoelectric Point: 6.8882

                                >NTDB_id=605205 NLY75_RS04415 WP_024381361.1 864830..866209(+) (ciaH) [Streptococcus suis T15]

MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD

SPTGEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM

SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYEATVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ

KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD

EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDEDGTIQIAANIKDKLVCFTVIDNGLGISDT

DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide

Download Length: 1380 bp

                                >NTDB_id=605205 NLY75_RS04415 WP_024381361.1 864830..866209(+) (ciaH) [Streptococcus suis T15]

ATGCCTAAGCGATTTAAAAAATTAATGTACACAGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT

TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA

TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT

AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG

AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA

CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG

TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC

GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAAGCGACAGTTGCTATTGTTATGGTATCAG

CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA

AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG

TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTGA

CAACAAATTTACTTAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT

GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT

TCGAACAGACAAGGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGAAGATGGGA

CAATTCAAATAGCAGCTAATATCAAGGACAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATACC

GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT

ATCTTTAGCTCAACAAATTATTAAGAATTTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG

AGGTACGTTTACCCAAATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ciaH	Streptococcus pneumoniae Rx1	49.345	99.782	0.492
ciaH	Streptococcus pneumoniae D39	49.345	99.782	0.492
ciaH	Streptococcus pneumoniae R6	49.345	99.782	0.492
ciaH	Streptococcus pneumoniae TIGR4	49.345	99.782	0.492
ciaH	Streptococcus mutans UA159	49.231	99.129	0.488

Detailed information NTG0605205