Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   K8P04_RS06215 Genome accession   NZ_CP082856
Coordinates   1230967..1231641 (+) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain FDAARGOS_1479     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1225967..1236641
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8P04_RS06180 (K8P04_06115) rpmG 1226884..1227054 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  K8P04_RS06185 (K8P04_06120) rpmB 1227066..1227302 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  K8P04_RS06190 (K8P04_06125) radC 1227516..1228181 (-) 666 WP_013527272.1 DNA repair protein RadC -
  K8P04_RS06195 (K8P04_06130) coaBC 1228344..1229546 (+) 1203 WP_015701964.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  K8P04_RS06200 (K8P04_06135) dut 1229594..1230049 (+) 456 WP_005631431.1 dUTP diphosphatase -
  K8P04_RS06205 (K8P04_06140) slmA 1230053..1230709 (+) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  K8P04_RS06210 (K8P04_06145) - 1230731..1230982 (+) 252 WP_005647999.1 YheU family protein -
  K8P04_RS06215 (K8P04_06150) crp 1230967..1231641 (+) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  K8P04_RS06220 (K8P04_06155) rlmC 1232006..1233184 (-) 1179 WP_015701965.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  K8P04_RS06225 (K8P04_06160) nagZ 1233181..1234233 (-) 1053 WP_041175055.1 beta-N-acetylhexosaminidase -
  K8P04_RS06230 (K8P04_06165) - 1234237..1234587 (-) 351 WP_005647993.1 YcfL family protein -
  K8P04_RS06235 (K8P04_06170) hinT 1234587..1234937 (-) 351 WP_005627389.1 purine nucleoside phosphoramidase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=603098 K8P04_RS06215 WP_005647998.1 1230967..1231641(+) (crp) [Haemophilus influenzae strain FDAARGOS_1479]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=603098 K8P04_RS06215 WP_005647998.1 1230967..1231641(+) (crp) [Haemophilus influenzae strain FDAARGOS_1479]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCTGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTTGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42