Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   K8P04_RS02600 Genome accession   NZ_CP082856
Coordinates   537148..538365 (-) Length   405 a.a.
NCBI ID   WP_077643717.1    Uniprot ID   -
Organism   Haemophilus influenzae strain FDAARGOS_1479     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 532148..543365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8P04_RS02560 (K8P04_02540) - 533041..533247 (-) 207 WP_015701556.1 heavy-metal-associated domain-containing protein -
  K8P04_RS02565 (K8P04_02545) - 533321..533527 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  K8P04_RS02570 (K8P04_02550) - 533601..533807 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  K8P04_RS02575 (K8P04_02555) - 533893..534099 (-) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  K8P04_RS02580 (K8P04_02560) cueR 534176..534562 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  K8P04_RS02585 (K8P04_02565) metJ 534576..534893 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  K8P04_RS02590 (K8P04_02570) rho 535141..536403 (+) 1263 WP_015701557.1 transcription termination factor Rho -
  K8P04_RS02595 (K8P04_02575) pilD 536459..537151 (-) 693 WP_041175037.1 A24 family peptidase Machinery gene
  K8P04_RS02600 (K8P04_02580) pilC 537148..538365 (-) 1218 WP_077643717.1 type II secretion system F family protein Machinery gene
  K8P04_RS02605 (K8P04_02585) pilB 538362..539756 (-) 1395 WP_077643716.1 GspE/PulE family protein Machinery gene
  K8P04_RS02610 (K8P04_02590) pilA 539753..540202 (-) 450 WP_077643715.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  K8P04_RS02615 (K8P04_02595) ampD 540317..540877 (+) 561 WP_014550480.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  K8P04_RS02620 (K8P04_02600) corC 541501..542400 (+) 900 WP_005648977.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46052.18 Da        Isoelectric Point: 9.6104

>NTDB_id=603074 K8P04_RS02600 WP_077643717.1 537148..538365(-) (pilC) [Haemophilus influenzae strain FDAARGOS_1479]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISHGLTHIKLQQNWQFGAKTKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGIPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=603074 K8P04_RS02600 WP_077643717.1 537148..538365(-) (pilC) [Haemophilus influenzae strain FDAARGOS_1479]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAGCCACGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAA
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGGCTGCTTCAATCTATTGAATCTGGCTT
AGCATTCTCACAAGCTATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTTGTTTGTAAAAAAATAGCCACACATCGTAGCCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTAGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCTGGCATTCCGCTTAATCAAGCGCTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTGATAGTGTAAGTAGCGATCTTTTTCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTGGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.044

100

0.973
  pilC Haemophilus influenzae Rd KW20

96.798

100

0.97
  pilC Glaesserella parasuis strain SC1401

38.75

98.765

0.383