Detailed information NTG0602946

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: NHZ68_RS16280
• Genome accession: NZ_CP099798
• Coordinates: 3559745..3561025 (-)
• Length: 426 a.a.
• NCBI ID: WP_003087924.1
• Uniprot ID: Q02KU5
• Organism: Pseudomonas aeruginosa strain PAO1-L
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3554745..3566025

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NHZ68_RS16270 (NHZ68_16270)	hupB	3556809..3557081 (-)	273	WP_003087931.1	nucleoid-associated protein HU-beta	-
NHZ68_RS16275 (NHZ68_16275)	lon	3557217..3559613 (-)	2397	WP_003087926.1	endopeptidase La	-
NHZ68_RS16280 (NHZ68_16280)	clpX	3559745..3561025 (-)	1281	WP_003087924.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
NHZ68_RS16285 (NHZ68_16285)	clpP	3561130..3561771 (-)	642	WP_003098129.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
NHZ68_RS16290 (NHZ68_16290)	tig	3561865..3563175 (-)	1311	WP_003087920.1	trigger factor	-
NHZ68_RS16295 (NHZ68_16295)	parR	3563407..3564114 (+)	708	WP_003098126.1	response regulator transcription factor ParR	-
NHZ68_RS16300 (NHZ68_16300)	parS	3564115..3565401 (+)	1287	WP_003113589.1	sensor histidine kinase ParS	-

Sequence

Protein

• Length: 426 a.a.
• Molecular weight: 46991.78 Da
• Isoelectric Point: 4.8347

>NTDB_id=602946 NHZ68_RS16280 WP_003087924.1 3559745..3561025(-) (clpX) [Pseudomonas aeruginosa strain PAO1-L]
MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSGHKLPAPKEIRTILDQYVI
GQERAKKVLAVAVYNHYKRLNQRDKKDDIELGKSNILMIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVD
TRNILFICGGAFAGLERVIQNRSARGGIGFNAEVRSQEMGKKVGEAFKEVEPEDLVKFGLIPEFVGRLPVIATLDELDEA
ALMQILTEPKNALTKQYAKLFEMEGVDLEFRPDALKAVARKALERKTGARGLRSILEGILLDTMYEIPSQQDVSKVVIDE
SVIDGSSQPLMIYENSEKPAKAAPEA

Nucleotide

• Length: 1281 bp

>NTDB_id=602946 NHZ68_RS16280 WP_003087924.1 3559745..3561025(-) (clpX) [Pseudomonas aeruginosa strain PAO1-L]
ATGACTGATACCCGCAACGGCGAGGACAACGGCAAGCTGCTGTATTGCTCCTTCTGCGGCAAGAGCCAGCACGAAGTGCG
CAAGTTGATTGCCGGCCCCTCGGTCTTTATCTGCGACGAGTGTGTCGACCTGTGCAATGACATCATCCGCGAGGAGGTGC
AGGAAGCGCAGGCGGAAAGTAGTGGGCACAAACTTCCGGCGCCGAAAGAGATCCGCACCATCCTCGATCAGTACGTGATC
GGGCAGGAGCGGGCCAAGAAGGTTCTGGCGGTAGCGGTATACAACCACTACAAGCGCCTCAACCAGCGTGACAAGAAGGA
CGATATCGAGCTCGGCAAGAGCAACATTCTGATGATCGGCCCAACCGGCTCGGGCAAGACCCTGCTGGCCGAGACCCTCG
CACGTCTGCTGAACGTGCCGTTCACCATCGCCGATGCGACCACGCTGACGGAAGCGGGCTACGTGGGCGAGGATGTCGAG
AACATCATCCAGAAACTCTTGCAGAAGTGCGATTACGATGTGGAGAAGGCCCAGATGGGCATCGTCTACATCGACGAGAT
CGACAAGATTTCCCGGAAATCGGACAACCCCTCCATCACTCGCGACGTCTCCGGCGAGGGTGTGCAGCAGGCCCTGCTGA
AGCTCATCGAGGGTACCGTTGCCTCGGTACCGCCGCAGGGCGGTCGCAAGCATCCGCAGCAGGAGTTCCTGCAGGTCGAT
ACGCGCAACATCCTGTTCATCTGCGGCGGCGCTTTCGCCGGTCTGGAGCGGGTCATCCAGAACCGTTCCGCGCGCGGCGG
CATCGGTTTCAATGCCGAAGTGCGCAGTCAGGAGATGGGCAAGAAGGTCGGCGAGGCGTTCAAGGAAGTCGAACCGGAAG
ATCTCGTCAAGTTCGGTCTTATTCCCGAGTTTGTAGGGCGTTTGCCGGTGATCGCGACTCTTGATGAGCTCGACGAGGCT
GCGCTCATGCAGATCCTGACCGAGCCGAAGAACGCTCTCACCAAGCAGTACGCCAAGCTGTTCGAAATGGAAGGCGTCGA
TCTCGAATTCCGTCCGGACGCACTCAAGGCGGTTGCCCGCAAGGCGCTCGAACGCAAGACCGGTGCACGTGGCTTGCGTT
CAATTCTCGAAGGTATCCTTCTCGATACCATGTACGAGATTCCCTCCCAGCAGGATGTCAGCAAGGTGGTCATCGATGAG
AGTGTCATCGATGGCTCGTCGCAACCCCTGATGATCTACGAGAACAGCGAAAAGCCAGCCAAGGCTGCGCCTGAGGCATG
A

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (14-51)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (113-311)

3D structure

• AlphaFold DB: Q02KU5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	60.934	95.54	0.582
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.198	94.836	0.523