Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   M5C73_RS09175 Genome accession   NZ_CP098790
Coordinates   1858894..1860264 (-) Length   456 a.a.
NCBI ID   WP_003130363.1    Uniprot ID   -
Organism   Lactococcus lactis strain WiKim0124     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1853894..1865264
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5C73_RS09160 (M5C73_09160) - 1855064..1856497 (-) 1434 WP_021722126.1 6-phospho-beta-glucosidase -
  M5C73_RS09165 (M5C73_09165) yidD 1856621..1856887 (-) 267 WP_012898265.1 membrane protein insertion efficiency factor YidD -
  M5C73_RS09170 (M5C73_09170) - 1857004..1858746 (-) 1743 WP_252160061.1 1-deoxy-D-xylulose-5-phosphate synthase -
  M5C73_RS09175 (M5C73_09175) ciaH 1858894..1860264 (-) 1371 WP_003130363.1 HAMP domain-containing sensor histidine kinase Regulator
  M5C73_RS09180 (M5C73_09180) ciaR 1860357..1861025 (-) 669 WP_021722129.1 response regulator transcription factor Regulator
  M5C73_RS09185 (M5C73_09185) - 1861203..1862177 (-) 975 WP_003130365.1 LacI family DNA-binding transcriptional regulator -
  M5C73_RS09190 (M5C73_09190) - 1862330..1864585 (-) 2256 WP_003130366.1 glycoside hydrolase family 65 protein -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 51300.85 Da        Isoelectric Point: 9.4537

>NTDB_id=601166 M5C73_RS09175 WP_003130363.1 1858894..1860264(-) (ciaH) [Lactococcus lactis strain WiKim0124]
MKKIIKKVKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLIEAANNQLGMNNSQD
SGYYGPNNSVIFYDSEGKSFIPSAGSNANISTNFGMSLLQKTMKFNENQINTIQTVSVKNPYGDNWHYRYLTTSQFIITN
TDGTVTPVYAQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSVIISLYLANWTLKPILAAYEKQKEFVENASHELRTPLAI
LQNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKF
SGHLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKART
RQKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=601166 M5C73_RS09175 WP_003130363.1 1858894..1860264(-) (ciaH) [Lactococcus lactis strain WiKim0124]
TTGAAGAAAATAATTAAAAAAGTTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAATTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTCTTTTTGATAGAAGCAGCGAATAATCAATTAGGAATGAATAATTCGCAAGAT
AGTGGCTATTACGGTCCCAATAATAGTGTAATTTTTTATGATTCAGAGGGTAAAAGTTTCATACCTTCAGCGGGTTCAAA
TGCAAATATAAGTACAAACTTTGGCATGAGCCTTCTGCAAAAAACAATGAAATTTAACGAAAATCAAATTAACACTATTC
AAACTGTTTCTGTAAAAAATCCTTATGGAGATAATTGGCACTATCGTTATCTGACAACATCACAATTTATTATTACAAAT
ACTGATGGAACAGTAACTCCGGTTTATGCACAAATTTTTTCAAATGTTGACCAAATTCAAGATGCCATGAGCCGAGCCAT
GTGGGTCATTGTGACAACAATGATTACTTTCTGGCTTCTGTCAGTAATTATTAGTCTATATCTTGCAAACTGGACATTGA
AACCAATTTTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTAGCAATC
TTGCAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACAGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTT
ATCAGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGC
CAGAGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTT
TCAGGCCATTTGAAATTAGATGGAACGATTAATTTGGACCAAGCCCTGATCAAACAATTGCTAACCATCTTATTTGATAA
TGCTCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGGGGATTCTTAGTTTTTGCTGTCG
CCGATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACG
CGTCAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGA
AGATAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGACAGCACAATTTCAAATCCTGCAAAAATTTTCC
AAAAGTTGTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(333-442)

His Kinase A (phospho-acceptor) domain (HisKA)

(223-289)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

48.837

94.298

0.461
  ciaH Streptococcus pneumoniae Rx1

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae D39

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae R6

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae TIGR4

44.321

98.465

0.436