Detailed information NTG0600644

Bioinformatically predicted

Overview

• Name: ruvA
• Type: Machinery gene
• Locus tag: NDQ65_RS08925
• Genome accession: NZ_CP098538
• Coordinates: 1700593..1701177 (+)
• Length: 194 a.a.
• NCBI ID: WP_003689924.1
• Uniprot ID: Q5F636
• Organism: Neisseria gonorrhoeae strain ATCC 49226
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1695593..1706177

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NDQ65_RS08890 (NDQ65_08830)	-	1696332..1696442 (+)	111	Protein_1709	IS5/IS1182 family transposase	-
NDQ65_RS08895 (NDQ65_08835)	-	1696523..1697311 (-)	789	WP_010359260.1	class I SAM-dependent methyltransferase	-
NDQ65_RS08900 (NDQ65_08840)	bioH	1697308..1698057 (-)	750	WP_010359261.1	pimeloyl-ACP methyl ester esterase BioH	-
NDQ65_RS08905 (NDQ65_08845)	-	1698056..1698781 (+)	726	WP_003694234.1	ComF family protein	-
NDQ65_RS08910 (NDQ65_08850)	trmL	1698846..1699310 (+)	465	WP_003689916.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
NDQ65_RS08915 (NDQ65_08855)	-	1699438..1700124 (+)	687	WP_010359263.1	septal ring lytic transglycosylase RlpA family protein	-
NDQ65_RS08920 (NDQ65_08860)	-	1700185..1700511 (+)	327	WP_003689921.1	PepSY domain-containing protein	-
NDQ65_RS08925 (NDQ65_08865)	ruvA	1700593..1701177 (+)	585	WP_003689924.1	Holliday junction branch migration protein RuvA	Machinery gene
NDQ65_RS08930 (NDQ65_08870)	-	1701177..1701314 (+)	138	WP_002235413.1	hypothetical protein	-
NDQ65_RS08935 (NDQ65_08875)	-	1701341..1703197 (+)	1857	WP_033910127.1	ABC transporter ATP-binding protein	-
NDQ65_RS08940 (NDQ65_08880)	rsgA	1703202..1704125 (+)	924	WP_082298544.1	ribosome small subunit-dependent GTPase A	-
NDQ65_RS08945 (NDQ65_08885)	-	1704238..1704462 (+)	225	WP_003689929.1	exodeoxyribonuclease VII small subunit	-
NDQ65_RS08950 (NDQ65_08890)	-	1704446..1705342 (+)	897	WP_003691917.1	polyprenyl synthetase family protein	-
NDQ65_RS08955 (NDQ65_08895)	-	1705459..1705758 (-)	300	WP_010359269.1	DUF2818 family protein	-

Sequence

Protein

• Length: 194 a.a.
• Molecular weight: 20729.99 Da
• Isoelectric Point: 6.4967

>NTDB_id=600644 NDQ65_RS08925 WP_003689924.1 1700593..1701177(+) (ruvA) [Neisseria gonorrhoeae strain ATCC 49226]
MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVGG
IGAKTALGILSAMTADELARAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHTVTDGLFAASPAADETEDIVSTLLA
LGYNEREAKAAVKGVPKGTDVGEGVRLALKNLLK

Nucleotide

• Length: 585 bp

>NTDB_id=600644 NDQ65_RS08925 WP_003689924.1 1700593..1701177(+) (ruvA) [Neisseria gonorrhoeae strain ATCC 49226]
ATGATCAGCAGACTGACCGGCAAACTGGTTGAAAAAAACCCTCCGCAAATCGTCATCGATGTCAACGGTGTCGGTTATGA
AGCCGACGTATCGATGCAGACCTTCTACAACCTGCCGCCCGTGGGTGAAAGCGTACAACTGTTTACCCAGCTTATCATTC
GGGAAGACGCACATCTTTTATTTGGTTTTGCCACTGCGGAAGAACGCAAGACCTTCCGCCAACTGATTAAGGTCGGCGGC
ATCGGCGCGAAAACGGCTTTGGGCATTTTGTCGGCGATGACGGCAGACGAGCTGGCGCGGGCGGTTGCAGAAGAAGATGT
CAAACGCCTCTCCTCCGCTCCGGGAATCGGCAAAAAAACCGCCGAACGTATGGTCTTGGAACTGCGCGGCAAGCTGGTCG
CGCATACGGTAACGGACGGGCTGTTTGCCGCCTCACCCGCCGCCGACGAAACGGAAGACATCGTCAGCACGCTGCTTGCG
CTGGGTTACAACGAACGCGAGGCAAAAGCGGCGGTCAAAGGCGTTCCGAAGGGGACGGACGTGGGCGAAGGCGTGCGCCT
TGCCCTGAAAAACCTGCTGAAATAA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix domain (HHH_5) (72-129)

• RuvA N terminal domain (RuvA_N) (1-62)

• RuvA, C-terminal domain (RuvA_C) (150-192)

3D structure

• AlphaFold DB: Q5F636

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvA	Streptococcus pneumoniae R6	38	100	0.392
ruvA	Streptococcus pneumoniae D39	38	100	0.392
ruvA	Streptococcus pneumoniae TIGR4	37.5	100	0.387
ruvA	Bacillus subtilis subsp. subtilis str. 168	34.951	100	0.371