Detailed information NTG0600587

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: K4A81_RS18230
• Genome accession: NZ_CP082262
• Coordinates: 3665478..3666641 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain BIM B-454D
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3660478..3671641

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K4A81_RS18200 (K4A81_18200)	-	3660743..3661162 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
K4A81_RS18205 (K4A81_18205)	comFC	3661236..3661925 (-)	690	WP_199449054.1	ComF family protein	Machinery gene
K4A81_RS18210 (K4A81_18210)	-	3661931..3662215 (-)	285	WP_003151389.1	late competence development ComFB family protein	-
K4A81_RS18215 (K4A81_18215)	comFA	3662273..3663658 (-)	1386	WP_029972824.1	DEAD/DEAH box helicase	Machinery gene
K4A81_RS18220 (K4A81_18220)	-	3663766..3664614 (-)	849	WP_003151387.1	DegV family protein	-
K4A81_RS18225 (K4A81_18225)	degU	3664712..3665401 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
K4A81_RS18230 (K4A81_18230)	degS	3665478..3666641 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
K4A81_RS18235 (K4A81_18235)	-	3666864..3667511 (+)	648	WP_007407485.1	YigZ family protein	-
K4A81_RS18240 (K4A81_18240)	-	3667516..3668730 (+)	1215	WP_014419013.1	LCP family protein	-
K4A81_RS18245 (K4A81_18245)	-	3668820..3669896 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
K4A81_RS18250 (K4A81_18250)	tuaH	3670028..3671224 (-)	1197	WP_121984549.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=600587 K4A81_RS18230 WP_007407484.1 3665478..3666641(-) (degS) [Bacillus velezensis strain BIM B-454D]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=600587 K4A81_RS18230 WP_007407484.1 3665478..3666641(-) (degS) [Bacillus velezensis strain BIM B-454D]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTGGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGGTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGATGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951