Detailed information NTG0600190

Bioinformatically predicted

Overview

• Name: ruvA
• Type: Machinery gene
• Locus tag: NDL73_RS06760
• Genome accession: NZ_CP098503
• Coordinates: 1290101..1290685 (+)
• Length: 194 a.a.
• NCBI ID: WP_003689924.1
• Uniprot ID: Q5F636
• Organism: Neisseria gonorrhoeae strain 10268
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1285101..1295685

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NDL73_RS06725 (NDL73_09120)	-	1285850..1285960 (+)	111	Protein_1297	IS5/IS1182 family transposase	-
NDL73_RS06730 (NDL73_09125)	-	1286041..1286829 (-)	789	WP_003697625.1	class I SAM-dependent methyltransferase	-
NDL73_RS06735 (NDL73_09130)	bioH	1286826..1287575 (-)	750	WP_010359261.1	pimeloyl-ACP methyl ester esterase BioH	-
NDL73_RS06740 (NDL73_09135)	-	1287574..1288289 (+)	716	Protein_1300	ComF family protein	-
NDL73_RS06745 (NDL73_09140)	trmL	1288354..1288818 (+)	465	WP_003689916.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
NDL73_RS06750 (NDL73_09145)	-	1288946..1289632 (+)	687	WP_003689919.1	septal ring lytic transglycosylase RlpA family protein	-
NDL73_RS06755 (NDL73_09150)	-	1289693..1290019 (+)	327	WP_003689921.1	PepSY domain-containing protein	-
NDL73_RS06760 (NDL73_09155)	ruvA	1290101..1290685 (+)	585	WP_003689924.1	Holliday junction branch migration protein RuvA	Machinery gene
NDL73_RS06765 (NDL73_09160)	-	1290685..1290822 (+)	138	WP_003689926.1	hypothetical protein	-
NDL73_RS06770 (NDL73_09165)	-	1290849..1292705 (+)	1857	WP_003700518.1	ABC transporter ATP-binding protein	-
NDL73_RS06775 (NDL73_09170)	rsgA	1292710..1293633 (+)	924	WP_003689928.1	ribosome small subunit-dependent GTPase A	-
NDL73_RS06780 (NDL73_09175)	-	1293746..1293970 (+)	225	WP_003689929.1	exodeoxyribonuclease VII small subunit	-
NDL73_RS06785 (NDL73_09180)	-	1293954..1294850 (+)	897	WP_003691917.1	polyprenyl synthetase family protein	-
NDL73_RS06790 (NDL73_09185)	-	1294967..1295266 (-)	300	WP_010359269.1	DUF2818 family protein	-

Sequence

Protein

• Length: 194 a.a.
• Molecular weight: 20729.99 Da
• Isoelectric Point: 6.4967

>NTDB_id=600190 NDL73_RS06760 WP_003689924.1 1290101..1290685(+) (ruvA) [Neisseria gonorrhoeae strain 10268]
MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVGG
IGAKTALGILSAMTADELARAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHTVTDGLFAASPAADETEDIVSTLLA
LGYNEREAKAAVKGVPKGTDVGEGVRLALKNLLK

Nucleotide

• Length: 585 bp

>NTDB_id=600190 NDL73_RS06760 WP_003689924.1 1290101..1290685(+) (ruvA) [Neisseria gonorrhoeae strain 10268]
ATGATCAGCAGACTGACCGGCAAACTGGTTGAAAAAAACCCTCCGCAAATCGTCATCGATGTCAACGGTGTCGGTTATGA
AGCCGACGTATCGATGCAGACCTTCTACAACCTGCCGCCCGTGGGTGAAAGCGTACAACTGTTTACCCAGCTTATCATTC
GGGAAGACGCACATCTTTTATTTGGTTTTGCCACTGCGGAAGAACGCAAGACCTTCCGCCAACTGATTAAGGTCGGCGGC
ATCGGCGCGAAAACGGCTTTGGGCATTTTGTCGGCGATGACGGCAGACGAGCTGGCGCGGGCGGTTGCAGAAGAAGATGT
CAAACGCCTCTCCTCCGCTCCGGGAATCGGCAAAAAAACCGCCGAACGTATGGTCTTGGAACTGCGCGGCAAGCTGGTCG
CGCATACGGTAACGGACGGGCTGTTTGCCGCCTCACCCGCCGCCGACGAAACGGAAGACATCGTCAGCACGCTGCTTGCG
CTGGGTTACAACGAACGCGAGGCAAAAGCGGCGGTCAAAGGCGTTCCGAAGGGGACGGACGTGGGCGAAGGCGTGCGCCT
TGCCCTGAAAAACCTGCTGAAATAA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix domain (HHH_5) (72-129)

• RuvA N terminal domain (RuvA_N) (1-62)

• RuvA, C-terminal domain (RuvA_C) (150-192)

3D structure

• AlphaFold DB: Q5F636

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvA	Streptococcus pneumoniae R6	38	100	0.392
ruvA	Streptococcus pneumoniae D39	38	100	0.392
ruvA	Streptococcus pneumoniae TIGR4	37.5	100	0.387
ruvA	Bacillus subtilis subsp. subtilis str. 168	34.951	100	0.371