Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   K6972_RS07405 Genome accession   NZ_CP082203
Coordinates   1495748..1497097 (-) Length   449 a.a.
NCBI ID   WP_002935841.1    Uniprot ID   G7SGQ2
Organism   Streptococcus suis strain NJ3     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1490748..1502097
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6972_RS07390 (K6972_07390) pbp2b 1491131..1493206 (-) 2076 WP_222812430.1 penicillin-binding protein PBP2B -
  K6972_RS07395 (K6972_07395) vga(F) 1493298..1494683 (-) 1386 WP_222812431.1 ABC-F type ribosomal protection protein Vga(F) -
  K6972_RS07400 (K6972_07400) vicX 1494938..1495741 (-) 804 WP_002935843.1 MBL fold metallo-hydrolase Regulator
  K6972_RS07405 (K6972_07405) micB 1495748..1497097 (-) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  K6972_RS07410 (K6972_07410) micA 1497090..1497794 (-) 705 WP_004298854.1 response regulator YycF Regulator
  K6972_RS07415 (K6972_07415) - 1497988..1498749 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  K6972_RS07420 (K6972_07420) - 1498760..1499599 (+) 840 WP_222812432.1 transporter substrate-binding domain-containing protein -
  K6972_RS07425 (K6972_07425) - 1499614..1500312 (+) 699 WP_004298848.1 amino acid ABC transporter permease -
  K6972_RS07430 (K6972_07430) - 1500327..1500986 (+) 660 WP_024384909.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51039.08 Da        Isoelectric Point: 4.5202

>NTDB_id=599941 K6972_RS07405 WP_002935841.1 1495748..1497097(-) (micB) [Streptococcus suis strain NJ3]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=599941 K6972_RS07405 WP_002935841.1 1495748..1497097(-) (micB) [Streptococcus suis strain NJ3]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCGAATTCTCTTAATGATTTGTCGGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACACGTCTGACTTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATTATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAATATCACCTGCTAGAGGTTTTAGATTTATCAGATCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGCGCTAATTTTGCAACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCTTGGTTGTAGTCTTACATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTTTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTCAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
TTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTCTATCGCGTGGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAGTATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SGQ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635