Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   K6972_RS02435 Genome accession   NZ_CP082203
Coordinates   463898..465190 (+) Length   430 a.a.
NCBI ID   WP_222812796.1    Uniprot ID   -
Organism   Streptococcus suis strain NJ3     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 458898..470190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6972_RS02410 (K6972_02410) - 459703..460344 (+) 642 WP_172078683.1 response regulator transcription factor -
  K6972_RS02415 (K6972_02415) - 460394..461794 (+) 1401 WP_222812792.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  K6972_RS02420 (K6972_02420) - 461796..462167 (+) 372 WP_222812793.1 S1 RNA-binding domain-containing protein -
  K6972_RS02425 (K6972_02425) cysK 462193..463119 (-) 927 WP_222812795.1 cysteine synthase A -
  K6972_RS02430 (K6972_02430) - 463209..463841 (-) 633 WP_161947046.1 YigZ family protein -
  K6972_RS02435 (K6972_02435) comFA/cflA 463898..465190 (+) 1293 WP_222812796.1 DEAD/DEAH box helicase Machinery gene
  K6972_RS02440 (K6972_02440) - 465183..465848 (+) 666 WP_222812798.1 ComF family protein -
  K6972_RS02445 (K6972_02445) hpf 465925..466467 (+) 543 WP_014637536.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48903.42 Da        Isoelectric Point: 9.0315

>NTDB_id=599926 K6972_RS02435 WP_222812796.1 463898..465190(+) (comFA/cflA) [Streptococcus suis strain NJ3]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYQAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQISGRVGRSMERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=599926 K6972_RS02435 WP_222812796.1 463898..465190(+) (comFA/cflA) [Streptococcus suis strain NJ3]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTATTGTCGAGCCTGCTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATTTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTGCATGGAGAGTCTGAACCTTATTTCCGAACTCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCGGATAATCCCA
TGCTCTATCAAGCAGCAGACAATGCGGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACAGCAACTTCAACAGATGAATTG
GATAAAAAAGTAAGAACAGGCAAATTAAGCCGTCTTAGTTTGCCAAGGCGATTTCATGGCAATCCGCTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTCCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGATTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATCGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTAACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGCGTCAAGTCTTGTTCAGATTTCGGGCCGGGTCGGCAGGAGTATGGAACGTCCGACTGGG
TTACTCCAGTTTTATCATGAAGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGATATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(91-235)

Helicase conserved C-terminal domain (Helicase_C)

(289-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

67.285

100

0.674
  comFA/cflA Streptococcus pneumoniae Rx1

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae D39

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae R6

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae TIGR4

66.589

100

0.667
  comFA/cflA Streptococcus mitis SK321

66.125

100

0.663
  comFA Lactococcus lactis subsp. cremoris KW2

53.904

92.326

0.498
  comFA Latilactobacillus sakei subsp. sakei 23K

37.819

100

0.379
  comFA Bacillus subtilis subsp. subtilis str. 168

37.349

96.512

0.36