Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccpA   Type   Regulator
Locus tag   K6976_RS07825 Genome accession   NZ_CP082202
Coordinates   1603796..1604800 (-) Length   334 a.a.
NCBI ID   WP_002935813.1    Uniprot ID   A0A0K2E7G3
Organism   Streptococcus suis strain SS389     
Function   regulate comCDE transcription and transformation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1586892..1610011 1603796..1604800 within 0


Gene organization within MGE regions


Location: 1586892..1610011
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6976_RS07770 (K6976_07770) - 1586892..1587809 (-) 918 WP_024401918.1 DUF1837 domain-containing protein -
  K6976_RS07775 (K6976_07775) - 1587921..1588148 (-) 228 WP_153057661.1 hypothetical protein -
  K6976_RS07780 (K6976_07780) thrS 1589198..1591147 (-) 1950 WP_222759207.1 threonine--tRNA ligase -
  K6976_RS07785 (K6976_07785) - 1591302..1591625 (-) 324 WP_407047428.1 MazG-like protein -
  K6976_RS07790 (K6976_07790) - 1591894..1592268 (-) 375 WP_029171456.1 hypothetical protein -
  K6976_RS07795 (K6976_07795) - 1592283..1593596 (-) 1314 WP_222759209.1 glycosyltransferase family 4 protein -
  K6976_RS07800 (K6976_07800) - 1593597..1594595 (-) 999 WP_014637671.1 glycosyltransferase family 4 protein -
  K6976_RS11150 - 1594699..1600293 (-) 5595 WP_407047436.1 DUF445 family protein -
  K6976_RS07815 (K6976_07815) - 1600716..1602077 (-) 1362 WP_024384329.1 HAMP domain-containing sensor histidine kinase -
  K6976_RS07820 (K6976_07820) - 1602078..1602728 (-) 651 WP_024384330.1 response regulator transcription factor -
  K6976_RS07825 (K6976_07825) ccpA 1603796..1604800 (-) 1005 WP_002935813.1 catabolite control protein A Regulator
  K6976_RS07830 (K6976_07830) - 1605010..1606095 (+) 1086 WP_024384331.1 Xaa-Pro peptidase family protein -
  K6976_RS11080 - 1606267..1606491 (-) 225 WP_315985281.1 LPXTG cell wall anchor domain-containing protein -

Sequence

Protein


Download         Length: 334 a.a.        Molecular weight: 36772.94 Da        Isoelectric Point: 5.5173

>NTDB_id=599891 K6976_RS07825 WP_002935813.1 1603796..1604800(-) (ccpA) [Streptococcus suis strain SS389]
MLNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANAYF
ATLAKGIDDIADMYKYNIVLANSDENDEKEINVVNTLFSKQVDGIIFMGYHLTDKIRAEFSRSRTPIVLAGTVDLEHQLP
SVNIDYAAASVDAVNLLAKNNKKIAFVSGPLVDDINGKVRFAGYKQGLKDNGIEFNEGLVFESKYKYEEGYALAERILNA
GATAAYVAEDEIAAGLLNGVSDMGVKVPEDFEIITSDDSLVTKFTRPNLTSINQPLYDIGAIAMRMLTKIMHKEELENRE
VVLNHGIKVRKSTK

Nucleotide


Download         Length: 1005 bp        

>NTDB_id=599891 K6976_RS07825 WP_002935813.1 1603796..1604800(-) (ccpA) [Streptococcus suis strain SS389]
ATGTTAAACACTGACGATACGGTAACGATTTATGACGTTGCCCGCGAAGCAGGTGTATCCATGGCGACAGTATCGCGCGT
GGTAAATGGGAATAAAAACGTAAAGGAAAATACTCGTAAAAAAGTATTAGAAGTCATCGACCGTTTGGATTATCGTCCGA
ATGCTGTTGCACGTGGCTTGGCCAGCAAGAAGACTACCACTGTGGGGGTTGTGATTCCAAATATTGCTAATGCTTATTTT
GCAACCTTGGCCAAAGGTATCGATGATATTGCCGATATGTACAAATACAATATCGTCCTAGCAAACAGTGATGAAAATGA
TGAGAAAGAAATCAATGTGGTAAATACCCTATTCTCAAAACAGGTGGACGGAATCATTTTCATGGGCTATCATTTGACAG
ACAAGATTCGTGCGGAGTTTTCACGCTCACGTACACCGATTGTTTTAGCTGGTACCGTGGACTTGGAGCACCAATTACCT
AGCGTCAATATTGACTATGCTGCCGCTAGTGTTGATGCAGTCAATCTATTAGCTAAGAACAACAAGAAAATTGCCTTTGT
ATCAGGGCCACTTGTAGATGACATCAACGGTAAAGTTCGTTTTGCAGGCTACAAACAAGGTTTGAAGGACAACGGAATCG
AGTTTAACGAAGGATTGGTTTTTGAATCCAAGTATAAATACGAGGAAGGCTACGCTCTAGCAGAACGTATTTTGAATGCC
GGAGCAACTGCAGCTTATGTTGCAGAAGATGAGATTGCTGCAGGTCTATTGAATGGTGTCAGTGATATGGGCGTCAAGGT
TCCAGAGGACTTTGAAATCATTACAAGTGATGATTCCCTAGTGACCAAGTTTACCCGTCCAAACCTGACCTCTATCAATC
AGCCACTATACGATATTGGTGCAATTGCTATGCGCATGCTTACCAAAATCATGCACAAGGAAGAGTTGGAAAACCGTGAG
GTAGTTCTTAACCACGGAATCAAAGTACGGAAATCAACTAAGTGA

Domains

Predicted by InterproScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(176-333)

Bacterial regulatory proteins, lacI family (LacI)

(9-54)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E7G3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccpA Streptococcus pneumoniae D39

80.18

99.701

0.799
  ccpA Streptococcus gordonii str. Challis substr. CH1

79.58

99.701

0.793
  ccpA Lactococcus lactis subsp. lactis strain DGCC12653

59.215

99.102

0.587