Detailed information NTG0599738

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: K6970_RS07720
• Genome accession: NZ_CP082199
• Coordinates: 1560487..1561536 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain Transconjugant cFJSM5
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1555487..1566536

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6970_RS07700 (K6970_07700)	nadE	1555893..1556717 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
K6970_RS07705 (K6970_07705)	-	1558013..1558540 (-)	528	WP_012027591.1	VanZ family protein	-
K6970_RS07710 (K6970_07710)	rlmN	1558537..1559649 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
K6970_RS07715 (K6970_07715)	-	1559658..1560299 (-)	642	WP_012027595.1	YutD-like domain-containing protein	-
K6970_RS07720 (K6970_07720)	sepM	1560487..1561536 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
K6970_RS07725 (K6970_07725)	coaD	1561523..1562011 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
K6970_RS07730 (K6970_07730)	rsmD	1562001..1562540 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
K6970_RS07735 (K6970_07735)	-	1562848..1563570 (-)	723	WP_012027598.1	lipoprotein	-
K6970_RS07740 (K6970_07740)	-	1563627..1564013 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
K6970_RS07745 (K6970_07745)	-	1564013..1564231 (-)	219	WP_004194736.1	YqgQ family protein	-
K6970_RS07750 (K6970_07750)	-	1564539..1565141 (-)	603	WP_012027601.1	response regulator transcription factor	-
K6970_RS07755 (K6970_07755)	-	1565138..1566232 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=599738 K6970_RS07720 WP_012775295.1 1560487..1561536(-) (sepM) [Streptococcus suis strain Transconjugant cFJSM5]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=599738 K6970_RS07720 WP_012775295.1 1560487..1561536(-) (sepM) [Streptococcus suis strain Transconjugant cFJSM5]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605