Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KFZ60_RS00170 Genome accession   NZ_CP098231
Coordinates   32197..32787 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain XJ34     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 27197..37787
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFZ60_RS00155 (KFZ60_00150) ilvN 28534..28824 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  KFZ60_RS00160 (KFZ60_00155) - 29086..30381 (+) 1296 WP_094770128.1 hypothetical protein -
  KFZ60_RS00165 (KFZ60_00160) - 30597..32033 (+) 1437 WP_088375981.1 hypothetical protein -
  KFZ60_RS00170 (KFZ60_00165) letA 32197..32787 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  KFZ60_RS00175 (KFZ60_00170) uhpB 32787..34289 (+) 1503 WP_024210882.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  KFZ60_RS00180 (KFZ60_00175) uhpC 34299..35618 (+) 1320 WP_000936560.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  KFZ60_RS00185 (KFZ60_00180) uhpT 35874..37265 (+) 1392 WP_088375980.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=598708 KFZ60_RS00170 WP_000633668.1 32197..32787(+) (letA) [Escherichia coli strain XJ34]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=598708 KFZ60_RS00170 WP_000633668.1 32197..32787(+) (letA) [Escherichia coli strain XJ34]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGTTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATTTCCGGTCTGGAACTGCTAAGCCAACTGCCGAAAGGTATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGTTGTAGCCCTGACGA
ACTGATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378