Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   KFZ54_RS03555 Genome accession   NZ_CP098227
Coordinates   732721..733380 (-) Length   219 a.a.
NCBI ID   WP_021574775.1    Uniprot ID   -
Organism   Escherichia coli strain XJ6-3     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 727721..738380
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFZ54_RS03530 (KFZ54_03525) - 728463..729410 (+) 948 WP_032281609.1 iron-siderophore ABC transporter substrate-binding protein -
  KFZ54_RS03535 (KFZ54_03530) - 729407..730294 (+) 888 WP_000614954.1 MurR/RpiR family transcriptional regulator -
  KFZ54_RS03540 (KFZ54_03535) ygiN 730339..730653 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  KFZ54_RS03545 (KFZ54_03540) mdaB 730684..731265 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  KFZ54_RS03550 (KFZ54_03545) qseC 731375..732724 (-) 1350 WP_000673365.1 quorum sensing histidine kinase QseC -
  KFZ54_RS03555 (KFZ54_03550) ciaR 732721..733380 (-) 660 WP_021574775.1 quorum sensing response regulator transcription factor QseB Regulator
  KFZ54_RS03560 (KFZ54_03555) ygiW 733532..733924 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  KFZ54_RS03565 (KFZ54_03560) ygiV 733977..734459 (+) 483 WP_000183494.1 GyrI-like domain-containing protein -
  KFZ54_RS03570 (KFZ54_03565) ygiS 734568..736175 (+) 1608 WP_047645899.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24704.67 Da        Isoelectric Point: 6.3527

>NTDB_id=598562 KFZ54_RS03555 WP_021574775.1 732721..733380(-) (ciaR) [Escherichia coli strain XJ6-3]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGCQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLILKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=598562 KFZ54_RS03555 WP_021574775.1 732721..733380(-) (ciaR) [Escherichia coli strain XJ6-3]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTTGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAATACTGAAACCAAAAGAATTTGCTCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365