Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   NBY12_RS19270 Genome accession   NZ_CP098223
Coordinates   4038369..4039028 (+) Length   219 a.a.
NCBI ID   WP_032303790.1    Uniprot ID   -
Organism   Escherichia coli strain Z0117EC0005     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 4033369..4044028
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NBY12_RS19250 (NBY12_19270) plsC 4033723..4034460 (-) 738 WP_032303788.1 1-acylglycerol-3-phosphate O-acyltransferase -
  NBY12_RS19255 (NBY12_19275) parC 4034694..4036952 (-) 2259 WP_001281881.1 DNA topoisomerase IV subunit A -
  NBY12_RS19260 (NBY12_19280) ygiV 4037290..4037772 (-) 483 WP_000793821.1 GyrI-like domain-containing protein -
  NBY12_RS19265 (NBY12_19285) ygiW 4037825..4038217 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  NBY12_RS19270 (NBY12_19290) ciaR 4038369..4039028 (+) 660 WP_032303790.1 quorum sensing response regulator transcription factor QseB Regulator
  NBY12_RS19275 (NBY12_19295) qseC 4039025..4040374 (+) 1350 WP_000673371.1 quorum sensing histidine kinase QseC -
  NBY12_RS19280 (NBY12_19300) ygiZ 4040420..4040752 (-) 333 WP_000912121.1 DUF2645 family protein -
  NBY12_RS19285 (NBY12_19305) mdaB 4041067..4041648 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  NBY12_RS19290 (NBY12_19310) ygiN 4041679..4041993 (+) 315 WP_000633737.1 putative quinol monooxygenase -
  NBY12_RS19295 (NBY12_19315) parE 4042041..4043933 (-) 1893 WP_000195280.1 DNA topoisomerase IV subunit B -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24691.62 Da        Isoelectric Point: 6.9850

>NTDB_id=598534 NBY12_RS19270 WP_032303790.1 4038369..4039028(+) (ciaR) [Escherichia coli strain Z0117EC0005]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQRETVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=598534 NBY12_RS19270 WP_032303790.1 4038369..4039028(+) (ciaR) [Escherichia coli strain Z0117EC0005]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCGGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGACGGTATTAATCCTGACTGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGAGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.885

100

0.393
  ciaR Streptococcus pneumoniae D39

37.885

100

0.393
  ciaR Streptococcus pneumoniae R6

37.885

100

0.393
  ciaR Streptococcus pneumoniae TIGR4

37.885

100

0.393
  ciaR Streptococcus mutans UA159

35.426

100

0.361