Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   NBY16_RS03810 Genome accession   NZ_CP098211
Coordinates   788422..789081 (-) Length   219 a.a.
NCBI ID   WP_048963581.1    Uniprot ID   -
Organism   Escherichia coli strain Z0117EC0040     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 783422..794081
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NBY16_RS03785 (NBY16_03785) parE 783513..785405 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  NBY16_RS03790 (NBY16_03790) ygiN 785453..785767 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  NBY16_RS03795 (NBY16_03795) mdaB 785798..786379 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  NBY16_RS03800 (NBY16_03800) ygiZ 786698..787030 (+) 333 WP_000912120.1 DUF2645 family protein -
  NBY16_RS03805 (NBY16_03805) qseC 787076..788425 (-) 1350 WP_000673354.1 quorum sensing histidine kinase QseC -
  NBY16_RS03810 (NBY16_03810) ciaR 788422..789081 (-) 660 WP_048963581.1 quorum sensing response regulator transcription factor QseB Regulator
  NBY16_RS03815 (NBY16_03815) ygiW 789233..789625 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  NBY16_RS03820 (NBY16_03820) ygiV 789678..790160 (+) 483 WP_000183494.1 GyrI-like domain-containing protein -
  NBY16_RS03825 (NBY16_03825) parC 790706..792964 (+) 2259 WP_001281881.1 DNA topoisomerase IV subunit A -
  NBY16_RS03830 (NBY16_03830) plsC 793198..793935 (+) 738 WP_000965703.1 1-acylglycerol-3-phosphate O-acyltransferase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24773.72 Da        Isoelectric Point: 6.6543

>NTDB_id=598150 NBY16_RS03810 WP_048963581.1 788422..789081(-) (ciaR) [Escherichia coli strain Z0117EC0040]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDVVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=598150 NBY16_RS03810 WP_048963581.1 788422..789081(-) (ciaR) [Escherichia coli strain Z0117EC0040]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCGCCTTATGATGTGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365