Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NBY18_RS00350 Genome accession   NZ_CP098206
Coordinates   70049..70639 (+) Length   196 a.a.
NCBI ID   WP_001332271.1    Uniprot ID   A0A0H2Z4C4
Organism   Escherichia coli strain Z0117EC0054     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 65049..75639
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NBY18_RS00315 (NBY18_00315) yidG 65341..65703 (+) 363 WP_001113443.1 DUF202 domain-containing protein -
  NBY18_RS00320 (NBY18_00320) yidF 65700..66197 (+) 498 WP_000148034.1 radical SAM protein -
  NBY18_RS00325 (NBY18_00325) emrD 66205..67389 (-) 1185 WP_001332269.1 multidrug efflux MFS transporter EmrD -
  NBY18_RS00330 (NBY18_00330) ysdE 67471..67545 (+) 75 WP_211180519.1 protein YsdE -
  NBY18_RS00335 (NBY18_00335) ivbL 67790..67888 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  NBY18_RS00340 (NBY18_00340) ilvB 67994..69682 (+) 1689 WP_000168473.1 acetolactate synthase large subunit -
  NBY18_RS00345 (NBY18_00345) ilvN 69686..69976 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  NBY18_RS00350 (NBY18_00350) letA 70049..70639 (+) 591 WP_001332271.1 transcriptional regulator UhpA Regulator
  NBY18_RS00355 (NBY18_00355) uhpB 70639..72141 (+) 1503 WP_033552009.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  NBY18_RS00360 (NBY18_00360) uhpC 72151..73470 (+) 1320 WP_001350834.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  NBY18_RS00365 (NBY18_00365) uhpT 73608..74999 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20836.26 Da        Isoelectric Point: 5.6059

>NTDB_id=597966 NBY18_RS00350 WP_001332271.1 70049..70639(+) (letA) [Escherichia coli strain Z0117EC0054]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGCGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=597966 NBY18_RS00350 WP_001332271.1 70049..70639(+) (letA) [Escherichia coli strain Z0117EC0054]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGTGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(136-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2Z4C4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378