Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NBY25_RS24715 Genome accession   NZ_CP098187
Coordinates   5086276..5086866 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain Z0117EC0117     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 5081276..5091866
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NBY25_RS24700 (NBY25_24695) uhpT 5081916..5083307 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  NBY25_RS24705 (NBY25_24700) uhpC 5083445..5084764 (-) 1320 WP_001536440.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  NBY25_RS24710 (NBY25_24705) uhpB 5084774..5086276 (-) 1503 WP_001314238.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  NBY25_RS24715 (NBY25_24710) letA 5086276..5086866 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  NBY25_RS24720 (NBY25_24715) ilvN 5086939..5087229 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  NBY25_RS24725 (NBY25_24720) ilvB 5087233..5088921 (-) 1689 WP_000168473.1 acetolactate synthase large subunit -
  NBY25_RS24730 (NBY25_24725) ivbL 5089027..5089125 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  NBY25_RS24735 (NBY25_24730) ysdE 5089370..5089444 (-) 75 WP_211180519.1 protein YsdE -
  NBY25_RS24740 (NBY25_24735) emrD 5089526..5090710 (+) 1185 WP_001304999.1 multidrug efflux MFS transporter EmrD -
  NBY25_RS24745 (NBY25_24740) yidF 5090718..5091215 (-) 498 WP_000148034.1 radical SAM protein -
  NBY25_RS24750 (NBY25_24745) yidG 5091212..5091574 (-) 363 WP_001113442.1 DUF202 domain-containing protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=597546 NBY25_RS24715 WP_000633668.1 5086276..5086866(-) (letA) [Escherichia coli strain Z0117EC0117]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=597546 NBY25_RS24715 WP_000633668.1 5086276..5086866(-) (letA) [Escherichia coli strain Z0117EC0117]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCACCGAAAACGGTACATGTCCATCGCGCCAACCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378