Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NAG72_RS03115 Genome accession   NZ_CP097884
Coordinates   658138..658728 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli str. K-12 substr. MG1655 strain K-12     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 653138..663728
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NAG72_RS03080 yidF 653253..653750 (+) 498 WP_000148061.1 radical SAM protein -
  NAG72_RS03085 emrD 653758..654942 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  NAG72_RS03090 ysdE 655024..655098 (+) 75 WP_211180519.1 protein YsdE -
  NAG72_RS03095 tisB 655222..655311 (-) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  NAG72_RS03100 ivbL 655876..655974 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  NAG72_RS03105 ilvB 656080..657768 (+) 1689 WP_000168475.1 acetolactate synthase large subunit -
  NAG72_RS03110 ilvN 657772..658062 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  NAG72_RS03115 letA 658138..658728 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  NAG72_RS03120 uhpB 658728..660230 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  NAG72_RS03125 uhpC 660240..661559 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  NAG72_RS03130 uhpT 661697..663088 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=597093 NAG72_RS03115 WP_000633668.1 658138..658728(+) (letA) [Escherichia coli str. K-12 substr. MG1655 strain K-12]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=597093 NAG72_RS03115 WP_000633668.1 658138..658728(+) (letA) [Escherichia coli str. K-12 substr. MG1655 strain K-12]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378