Detailed information NTG0596599

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: M9H69_RS04970
• Genome accession: NZ_CP097843
• Coordinates: 959139..961127 (+)
• Length: 662 a.a.
• NCBI ID: WP_250316097.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain HP01
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 954139..966127

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M9H69_RS04955 (M9H69_04955)	-	955031..955771 (-)	741	WP_007516801.1	amino acid ABC transporter ATP-binding protein	-
M9H69_RS04960 (M9H69_04960)	-	955771..957936 (-)	2166	WP_250316095.1	ABC transporter substrate-binding protein/permease	-
M9H69_RS04965 (M9H69_04965)	-	958109..959062 (+)	954	WP_250316096.1	CPBP family intramembrane glutamic endopeptidase	-
M9H69_RS04970 (M9H69_04970)	uvrB	959139..961127 (+)	1989	WP_250316097.1	excinuclease ABC subunit UvrB	Machinery gene
M9H69_RS04975 (M9H69_04975)	-	961819..962139 (+)	321	WP_250316171.1	hypothetical protein	-
M9H69_RS04980 (M9H69_04980)	-	962159..962626 (+)	468	WP_250316098.1	8-oxo-dGTP diphosphatase	-
M9H69_RS04985 (M9H69_04985)	-	962623..962736 (-)	114	Protein_933	3H domain-containing protein	-
M9H69_RS04990 (M9H69_04990)	-	962793..963566 (+)	774	WP_250316099.1	class I SAM-dependent methyltransferase	-
M9H69_RS04995 (M9H69_04995)	-	963682..963831 (+)	150	Protein_935	NUDIX hydrolase	-
M9H69_RS05000 (M9H69_05000)	-	963828..964343 (-)	516	WP_250316100.1	transcription repressor NadR	-
M9H69_RS05005 (M9H69_05005)	-	964355..964882 (-)	528	WP_000354636.1	ECF transporter S component	-
M9H69_RS05010 (M9H69_05010)	-	965062..965625 (-)	564	WP_001042726.1	ECF transporter S component	-

Sequence

Protein

• Length: 662 a.a.
• Molecular weight: 75807.98 Da
• Isoelectric Point: 4.6080

>NTDB_id=596599 M9H69_RS04970 WP_250316097.1 959139..961127(+) (uvrB) [Streptococcus oralis strain HP01]
MINRITDNKFKLVSKYEPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
MTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVTKEEDKEIDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKAMG

Nucleotide

• Length: 1989 bp

>NTDB_id=596599 M9H69_RS04970 WP_250316097.1 959139..961127(+) (uvrB) [Streptococcus oralis strain HP01]
ATGATCAATCGGATTACAGATAATAAATTTAAACTAGTATCAAAATACGAACCTTCAGGAGATCAACCCCAGGCAATTGA
GCAGTTGGTTGATAATATCGAGGGTGGAGAAAAGGCTCAGATTCTGATGGGGGCGACGGGTACAGGGAAGACCTATACCA
TGAGTCAAGTCATTTCCAAAGTCAATAAGCCAACTTTGGTCATTGCGCATAACAAAACCCTAGCTGGTCAGCTCTACGGA
GAGTTCAAGGAATTTTTCCCTGAAAATGCTGTTGAGTACTTTGTGTCTTATTATGATTATTACCAACCCGAGGCTTATGT
CCCTTCGAGCGATACCTATATTGAGAAGGATAGCTCTGTCAATGATGAGATTGACAAGCTCCGTCACTCAGCGACTTCGG
CTCTTCTGGAGCGTAACGATGTCATCGTCGTGGCTTCAGTCTCTTGTATCTATGGTTTGGGTTCGCCAAAGGAATACGCA
GATAGTGTCGTTAGTCTCCGTCCTGGTCTTGAGATTTCTCGTGATAAACTCTTGAATGACTTGGTTGATATCCAGTTTGA
ACGTAATGACATTGATTTCCAACGAGGAAGATTTCGCGTTCGCGGGGATGTGGTGGAGATTTTTCCAGCTTCCCGTGATG
AACACGCTTTTCGAGTAGAGTTCTTCGGAGATGAAATTGACCGTATCCGAGAAGTTGAGGCTCTGACTGGTCAGGTATTA
GGTGAAGTGGATCATCTGGCAATTTTCCCTGCGACTCACTTTGTGACCAATGACGACCACATGGAAGTTGCTATTGCCAA
GATTCAGGCTGAGTTGGAGGAGCAGTTAGCTGTCTTTGAAAAGGAAGGCAAACTGCTAGAGGCCCAGCGTTTGAAACAGC
GGACAGAGTATGATATTGAGATGTTACGTGAGATGGGTTATACAAATGGGGTTGAGAACTACTCACGCCACATGGATGGT
CGTAGTGAAGGGGAGCCTCCTTATACGCTTCTCGACTTCTTCCCAGATGATTTTTTGATCATGATTGATGAAAGCCACAT
GACCATGGGGCAGATCAAGGGCATGTACAATGGAGACCGTTCTCGTAAGGAAATGCTGGTAAATTATGGTTTCCGTTTGC
CATCAGCCTTGGACAATCGACCTCTTCGTCGTGAAGAGTTTGAAAGTCACGTTCATCAGATTGTTTACGTTTCAGCGACA
CCAGGTGATTATGAAAATGAACAGACCGAGACAGTGATTGAGCAAATCATTCGTCCAACAGGGCTTCTAGACCCAGAGGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGACCTATTGGGTGAAATCAATGCCCGTGTTGAAAAGAATGAACGAACCT
TTATCACAACCTTGACCAAGAAGATGGCAGAAGACTTGACCGACTACTTCAAGGAAATGGGCATCAAGGTCAAGTATATG
CACTCGGACATCAAGACCTTGGAGCGGACGGAGATTATCCGTGACCTGCGCTTGGGTGTATTTGATGTCTTAGTCGGAAT
CAACCTGCTCCGCGAAGGGATTGACGTTCCTGAGGTAAGCTTGGTTGCCATTCTCGATGCTGATAAGGAAGGTTTCCTTC
GTAACGAACGTGGCCTCATCCAGACCATTGGTCGTGCTGCCCGTAATAGCGAAGGGCATGTGATTATGTATGCGGACACG
ATGACTCAGTCTATGCAACGCGCTATCGATGAAACGGCTCGCCGTCGGAAAATCCAGATGGCATATAATGAAGAACATGG
TATCGTACCTCAGACAATCAAGAAAGAAATCCGTGACCTGATTGCCGTAACCAAGGCAGTTACCAAGGAAGAGGACAAGG
AAATTGACATCAACAGCCTCAACAAGCAAGAGCGCAAAGAACTCGTCAAGAAACTGGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTGGCAGCTCAGATCCGTGATATGATGCTGGAAGTCAAGGCGATGGGGTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• Helicase conserved C-terminal domain (Helicase_C) (443-549)

• UvrB interaction domain (UvrB_inter) (164-254)

• UvrB/uvrC motif (UVR) (626-659)

• Type III restriction enzyme, res subunit (ResIII) (17-143)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	98.941	99.849	0.988
uvrB	Streptococcus pneumoniae D39	98.941	99.849	0.988
uvrB	Streptococcus pneumoniae TIGR4	98.79	99.849	0.986