Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   M6G44_RS05525 Genome accession   NZ_CP097377
Coordinates   1216062..1216727 (+) Length   221 a.a.
NCBI ID   WP_005619495.1    Uniprot ID   A0ABM6X4X3
Organism   Actinobacillus pleuropneumoniae strain GD2107     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1211062..1221727
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M6G44_RS05495 (M6G44_05495) fabB 1211795..1213012 (+) 1218 WP_005615403.1 beta-ketoacyl-ACP synthase I -
  M6G44_RS05500 (M6G44_05500) - 1213207..1214416 (+) 1210 Protein_1077 IS3 family transposase -
  M6G44_RS05505 (M6G44_05505) - 1214563..1214910 (+) 348 WP_012478485.1 NirD/YgiW/YdeI family stress tolerance protein -
  M6G44_RS05510 (M6G44_05510) - 1214966..1215358 (+) 393 WP_005617551.1 hypothetical protein -
  M6G44_RS05515 (M6G44_05515) - 1215367..1215558 (+) 192 WP_237593140.1 NirD/YgiW/YdeI family stress tolerance protein -
  M6G44_RS05520 (M6G44_05520) - 1215599..1215973 (+) 375 WP_005615415.1 NirD/YgiW/YdeI family stress tolerance protein -
  M6G44_RS05525 (M6G44_05525) ciaR 1216062..1216727 (+) 666 WP_005619495.1 response regulator Regulator
  M6G44_RS05530 (M6G44_05530) - 1216720..1218096 (+) 1377 WP_005597899.1 ATP-binding protein -
  M6G44_RS05535 (M6G44_05535) - 1218144..1218704 (-) 561 WP_005603079.1 YtfJ family protein -
  M6G44_RS05540 (M6G44_05540) yajC 1218898..1219194 (+) 297 WP_005597904.1 preprotein translocase subunit YajC -
  M6G44_RS05545 (M6G44_05545) secD 1219221..1221068 (+) 1848 WP_012478486.1 protein translocase subunit SecD -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25153.05 Da        Isoelectric Point: 5.7945

>NTDB_id=594796 M6G44_RS05525 WP_005619495.1 1216062..1216727(+) (ciaR) [Actinobacillus pleuropneumoniae strain GD2107]
MRILLIEDDKLIGDGLKLGLTKQNFVVDWFQDGKLGFEALFSTEYDAVVLDLTLPKMDGLAILKNWRKENLDIPVLILTA
RDTLDERILGFNSGADDYLCKPFALMEVVVRLQALIRRRYKQSSTEITLGDLTIDSSTHKVTLADKEINLTSKEFQLLLL
FASNKDRVLTRSAIEEKLYSWDNDVSSNAMEVYIHNLRKKLGKEWIKTVHGIGYKIGNSDA

Nucleotide


Download         Length: 666 bp        

>NTDB_id=594796 M6G44_RS05525 WP_005619495.1 1216062..1216727(+) (ciaR) [Actinobacillus pleuropneumoniae strain GD2107]
ATGCGTATTCTACTGATTGAAGACGACAAACTAATCGGTGACGGCTTAAAGCTGGGACTAACCAAACAAAATTTTGTCGT
TGATTGGTTCCAAGACGGCAAATTAGGCTTTGAAGCGTTATTCTCTACCGAATATGATGCGGTCGTTTTGGATTTAACGT
TACCTAAAATGGACGGTTTAGCCATTCTGAAAAATTGGCGTAAAGAAAATCTGGATATTCCGGTTTTAATCTTAACCGCA
AGGGATACGTTAGACGAAAGAATATTGGGATTTAATTCCGGTGCGGACGATTATCTCTGTAAGCCGTTTGCATTAATGGA
AGTGGTCGTCCGTTTACAAGCTCTAATTCGCCGCCGTTATAAACAGAGTTCCACCGAAATTACTCTCGGTGATCTGACGA
TTGACAGCAGTACCCACAAAGTAACCCTTGCCGATAAAGAAATCAATTTAACCTCGAAAGAATTTCAATTGCTGTTACTG
TTTGCCAGTAATAAAGATCGTGTTTTGACGCGTTCCGCTATCGAAGAAAAATTATACAGTTGGGATAACGACGTCAGCAG
TAACGCTATGGAAGTTTATATCCATAATTTACGTAAAAAACTCGGTAAAGAATGGATCAAAACCGTACACGGCATAGGTT
ATAAAATAGGAAATTCAGATGCTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.778

100

0.385
  ciaR Streptococcus pneumoniae D39

37.778

100

0.385
  ciaR Streptococcus pneumoniae R6

37.778

100

0.385
  ciaR Streptococcus pneumoniae TIGR4

37.778

100

0.385
  ciaR Streptococcus mutans UA159

37.9

99.095

0.376