Detailed information NTG0594082

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JMO16_RS10220
• Genome accession: NZ_CP080566
• Coordinates: 2044758..2045801 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain HL20835 isolate HL20835
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2039758..2050801

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMO16_RS10190 (JMO16_10190)	-	2040179..2041435 (-)	1257	WP_001795108.1	aminopeptidase	-
JMO16_RS10195 (JMO16_10195)	-	2041438..2041638 (-)	201	WP_000180460.1	DUF1128 family protein	-
JMO16_RS10200 (JMO16_10200)	-	2041785..2042249 (+)	465	WP_042109418.1	low molecular weight protein-tyrosine-phosphatase	-
JMO16_RS10205 (JMO16_10205)	-	2042256..2042531 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
JMO16_RS10210 (JMO16_10210)	-	2042809..2044026 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
JMO16_RS10215 (JMO16_10215)	vraR	2044139..2044768 (-)	630	WP_042109421.1	two-component system response regulator VraR	Regulator
JMO16_RS10220 (JMO16_10220)	vraS	2044758..2045801 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
JMO16_RS10225 (JMO16_10225)	liaF	2045798..2046499 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
JMO16_RS10230 (JMO16_10230)	-	2046514..2046900 (-)	387	WP_001110179.1	hypothetical protein	-
JMO16_RS10235 (JMO16_10235)	map	2047117..2047875 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
JMO16_RS10240 (JMO16_10240)	-	2048406..2048534 (+)	129	WP_256969316.1	aromatic acid exporter family protein	-
JMO16_RS10245 (JMO16_10245)	-	2048624..2049943 (+)	1320	WP_001557163.1	ISL3-like element IS1181 family transposase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=594082 JMO16_RS10220 WP_001017131.1 2044758..2045801(-) (vraS) [Staphylococcus aureus strain HL20835 isolate HL20835]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=594082 JMO16_RS10220 WP_001017131.1 2044758..2045801(-) (vraS) [Staphylococcus aureus strain HL20835 isolate HL20835]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1